Cas 708293-58-7,3-(4-fluorophenyl)-2-{[4-(2-furoyl)-1-piperazinyl]methyl}-4(3H)-quinazolinone

708293-58-7

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Basic information

Product Name: 3-(4-fluorophenyl)-2-{[4-(2-furoyl)-1-piperazinyl]methyl}-4(3H)-quinazolinone
Synonyms: 3-(4-fluorophenyl)-2-{[4-(2-furoyl)-1-piperazinyl]methyl}-4(3H)-quinazolinone
CAS NO:708293-58-7
Molecular Formula: C₂₄H₂₁FN₄O₃
Molecular Weight: 432.4469432
EINECS: N/A
Product Categories: N/A
Mol File: 708293-58-7.mol

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 3-(4-fluorophenyl)-2-{[4-(2-furoyl)-1-piperazinyl]methyl}-4(3H)-quinazolinone(CAS DataBase Reference)
NIST Chemistry Reference: 3-(4-fluorophenyl)-2-{[4-(2-furoyl)-1-piperazinyl]methyl}-4(3H)-quinazolinone(708293-58-7)
EPA Substance Registry System: 3-(4-fluorophenyl)-2-{[4-(2-furoyl)-1-piperazinyl]methyl}-4(3H)-quinazolinone(708293-58-7)

Safety Data

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Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 708293-58-7(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 708293-58-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,8,2,9 and 3 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 708293-58:
(8*7)+(7*0)+(6*8)+(5*2)+(4*9)+(3*3)+(2*5)+(1*8)=177
177 % 10 = 7
So 708293-58-7 is a valid CAS Registry Number.

708293-58-7Upstream product

708293-58-7Downstream Products

708293-58-7Relevant academic research and scientific papers

Synthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1α inhibitors

Huang, Wenwei,Huang, Ruili,Attene-Ramos, Matias S.,Sakamuru, Srilatha,Englund, Erika E.,Inglese, James,Austin, Christopher P.,Xia, Menghang

, p. 5239 - 5243 (2011/10/02)

Quinazolin-4-one 1 was identified as an inhibitor of the HIF-1α transcriptional factor from a high-throughput screen. HIF-1α up-regulation is common in many cancer cells. In this Letter, we describe an efficient one-pot sequential reaction for the synthes

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