70849-16-0

Usage

Uses

Used in Biochemical Research:
D-MANNOSE-2-13C is used as a labeled analog for studying the role of D-mannose in various cellular processes, including glycosylation of proteins and other molecules. The incorporation of carbon-13 allows researchers to track its metabolic pathways and interactions with other biomolecules.
Used in Infant Formulas:
D-MANNOSE-2-13C is used in infant formulas as a component of the glycosylation process. It plays a crucial role in the N and O glycosylation of bovine whey protein products, which are essential for the proper functioning of the immune system and overall health in infants.
Used in Immunology Research:
D-MANNOSE-2-13C is used as a labeled analog in the study of O-glycosylation of the T helper cell-derived cytokine interleukin-17A. This cytokine is an important cell-signaling molecule involved in immune responses, and understanding its glycosylation can provide insights into the regulation of immune system function.

Upstream product

• 70849-31-9 <1-13C>-D-mannose 

Downstream Products

• 79-14-1 glycolic Acid 
• 473-81-4 D-glyceric acid 
• 276672-31-2 C⁽¹³⁾CH₂O₄ 
• 488-16-4 D-erythronic acid 
• 1185549-56-7 C₃⁽¹³⁾CH₆O₆ 
• 1185549-15-8 C₅⁽¹³⁾CH₁₀O₆ 
• 1185549-35-2 arabinonic acid-1-¹³C 
• 1185548-98-4 C₅⁽¹³⁾CH₁₀O₇ 
• 1185549-07-8 C₅⁽¹³⁾CH₁₀O₇ 
• 1185548-89-3 C₅⁽¹³⁾CH₁₂O₇ 
• 1185549-32-9 C₅⁽¹³⁾CH₁₀O₈ 
• 70849-23-9 [1-⁽¹³⁾C]-D-arabinose 
• 70849-31-9 <1-13C>-D-mannose 
• 1633-56-3 (¹³C)-formic acid 

Relevant academic research and scientific papers

Paramolybdate anion-exchange resin, an improved catalyst for the C-1-C-2 rearrangement and 2-epimerization of aldoses.

Aqueous solutions of molybdate at 90 degrees bring about the inversion of the C-1-C-2 fragment of aldoses having four or more carbon atoms, generating thermodynamically equilibrated mixtures of the starting aldose and its 2-epimer. In some cases, notably with the aldopentoses, substantial proportions of the 3-epimers are produced, as well as 2-epimers that have not undergone inversion of the C-1-C-2 fragment. These side-reactions can be controlled by using the paramolybdate form of an anion-exchange resin (AG MP-1) together with the formate form of the same resin. The latter acts to scavenge unbound molybdate and paramolybdate anions that appear to be responsible for the side reactions.