D-MANNOSE-2-13C

Base Information

• Chemical Name: D-MANNOSE-2-13C
• CAS No.: 70849-16-0
• Molecular Formula: C₆H₁₂O₆
• Molecular Weight: 181.147
• Mol file: 70849-16-0.mol

Synonyms:D-[2-13C]MANNOSE;D-MANNOSE-2-13C

Chemical Property of D-MANNOSE-2-13C

Chemical Property:

• Melting Point: 133 °C(lit.)
• PSA: 110.38000
• LogP: -3.22140

Purity/Quality:

98% ^*data from raw suppliers

D-Mannose-2-13C ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: D-MANNOSE-2-13C is a carbohydrate that is important in the glycosylation of molecules in a variety of cellular processes. It is involved in N and O glycosylation of bovine why protein products, used in infant formulas. It is also responsible for the O-glycosylation of the T helper cell-derived cytokine interlukin-17A, an important cell-signaling molecule. This is the labeled analog.

Technology Process of D-MANNOSE-2-13C

There total 1 articles about D-MANNOSE-2-13C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

<1-13C>-D-mannose (70849-31-9,478519-02-7) → [1-13C]D-glucose (40762-22-9,478519-02-7) + D-<2-13C>glucose (70849-16-0,83379-35-5,83379-36-6,70849-17-1,478529-73-6)

Guidance literature:

molybdenum(VI) oxide; In water; at 92 ℃;

DOI:10.1016/S0008-6215(00)90268-4

Reference yield: 60.0%

benzyl bromide (100-39-0) + D-<2-13C>glucose (70849-16-0,83379-35-5,83379-36-6,70849-17-1,478529-73-6) → C2-13C-tri-O-benzyl-D-glucal (444313-78-4)

Guidance literature:

Multistep reaction.;

DOI:10.1021/ja026281n

Reference yield:

D-<2-13C>glucose (70849-16-0,83379-35-5,83379-36-6,70849-17-1,478529-73-6) → glycolic Acid (79-14-1) + D-glyceric acid (473-81-4,600-19-1,6000-40-4,28305-26-2,118916-26-0) + C(13)CH2O4 (276672-31-2) + C4(13)CH8O7

Guidance literature:

With sodium hydroxide; sulfuric acid; ozone; In water; at 20 ℃; pH=2.5;

DOI:10.1016/j.carres.2009.05.012

upstream raw materials:

<1-13C>-D-mannose

Downstream raw materials:

C₂-¹³C-tri-O-benzyl-D-glucal

glycolic Acid

D-glyceric acid

C⁽¹³⁾CH₂O₄

Refernces