70872-16-1Relevant academic research and scientific papers
Preparation of N-alkyl-substituted 3,5-dinitroanilines by amination of 1,3,5-trinitrobenzene
Chao, Qian,Jinqiang, Liu,Xinzhi, Chen
experimental part, p. 70 - 71 (2009/07/18)
Highly efficient amination of 1,3,5-trinitrobenzene by a number of simple aliphatic amines to form the corresponding N-alkyl-substituted 3,5-dinitroanilines has been achieved.
Basic Hydrolysis of Some Alkyl and Phenyl N-Aryl-N-methylcarbamates.
Broxton, Trevor J.
, p. 2203 - 2209 (2007/10/02)
Rate constants for the basic hydrolysis of methyl, ethyl and phenyl N-aryl-N-methylcarbamates in the presence and absence of micelles of cetyltrimethylammonium bromide are reported.Hammett plots for the methyl aand ethyl carbamates were curved, and this is explained by consideration of the competition between C-N and C-OR bond breaking for decomposition of the tetrahedral intermediate.In one case (p-nitro-substituted), rate-determining formation of the tetrahedral intermediate is suggested, whereas for other compounds rate-determining C-N bond breaking or C-OR bond bre aking is proposed.Micellar catalysis for each of the reactions is reported, and large catalysis (x 50) was observed for compounds where C-N bond breaking was kinetically significant.This is compared with results in the literature for amide and ester hydrolysis.Whereas, for ester hydrolysis, loss of alkoxide ion from the tetrahedral intermediate is favoured over loss of hydroxide ion, in carbamate hydrolysis, loss of hydroxide ions is favoured.A possible reason for this reversal of nucleofugicity of OH- and OR- is proposed.
Method of preventing coccidiosis with 3,5-dinitroaniline derivatives and veterinary compositions containing such derivatives
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, (2008/06/13)
Compounds of the formula: SPC1 Wherein R1 represents hydrogen, methyl, ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl or sec-butyl, R2 represents hydrogen or alkyl of 1 through 4 carbon atoms or cycloalkyl of 3 or 4 carbon atoms, an
