70898-14-5Relevant academic research and scientific papers
A pyrene derivative for Hg2+-selective fluorescent sensing and its application in in vivo imaging
Wang, Guang Ke,Mi, Qi Li,Zhao, Li Yun,Hu, Jun Jie,Guo, Lin E,Zou, Xiao Ju,Liu, Bo,Xie, Xiao Guang,Zhang, Jun Feng,Zhao, Qi Hua,Zhou, Ying
, p. 744 - 748 (2014)
An Hg2+-selective fluorescent sensor (1) bearing pyrene as a fluorophore was synthesized. A sandwich-stacking binding mode was formed during the binding process, which increased the excimer fluorescence 22-fold at 490 nm. Compound 1 was successfully applied in in vivo imaging to trace the enrichment and distribution of mercury in the nervous system, digestive system, and reproductive system of Caenorhabditis elegans, as well as the organs of zebrafish. A bright sandwich: An Hg2+-selective fluorescent sensor (1) bearing pyrene as a fluorophore was synthesized. A sandwich-stacking binding mode was formed during the binding process, which increased the excimer fluorescence 22-fold at 490 nm (see figure). Compound 1 was successfully applied in in vivo imaging to trace the enrichment and distribution of mercury in Caenorhabditis elegans. Copyright
Photoionophores derived from crown ether polycarboxylic acids: synthesis, ion binding, and spectroscopic characterization
Fyles,Suresh
, p. 1246 - 1253 (1994)
Three types of potential photoionophores based on polycarboxylic acid crown ethers were prepared, and their cation complexation behaviours and spectroscopic properties were surveyed. The first type were neural macropolycyclic hosts prepared by capping acr
Preparation of Carbodiimides with One-Handed Axial Chirality
Taniguchi, Tohru,Suzuki, Takahiro,Satoh, Haruka,Shichibu, Yukatsu,Konishi, Katsuaki,Monde, Kenji
, p. 15577 - 15581 (2018/11/23)
The axial chirality of carbodiimide was proposed in 1932, but the synthesis of carbodiimide with one-handed axial chirality has not been achieved because of the low barrier of racemization. This work presents a strategy to use a conformationally restrained cyclic structure for creating carbodiimides whose biases of the axial chirality (labeled as SNCN/RNCN) are higher than 100:1, as determined by vibrational circular dichroism spectroscopy and density functional theory calculations.
Synthesis of biphenyl-based ligand: Application in copper-mediated chemoselective michael reaction
Sundar, M. Shyam,Bedekar, Ashutosh V.
, p. 3582 - 3593 (2015/08/11)
A biphenyl-based ligand attached was synthesized and screened in copper-mediated Michael reaction. The catalyst system works well with carbon or sulfur nucleophiles as Michael donors and cyclohexenone or chalcones as the acceptors under mild and neutral r
Design, synthesis and in vitro evaluation of novel bivalent S-adenosylmethionine analogues
Joce, Catherine,White, Rebecca,Stockley, Peter G.,Warriner, Stuart,Turnbull, W. Bruce,Nelson, Adam
, p. 278 - 284 (2012/03/11)
In optimal cases, bivalent ligands can bind with exceptionally high affinity to their protein targets. However, designing optimised linkers, that orient the two binding groups perfectly, is challenging, and yet crucial in both fragment-based ligand design
