709030-49-9

Basic information

• Product Name: 4-(N,N-dimethylamino)-8-methoxy-2-phenylquinazoline
• Synonyms: 4-(N,N-dimethylamino)-8-methoxy-2-phenylquinazoline
• CAS NO: 709030-49-9
• Molecular Weight: 279.341
• Mol File: 709030-49-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(N,N-dimethylamino)-8-methoxy-2-phenylquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(N,N-dimethylamino)-8-methoxy-2-phenylquinazoline(709030-49-9)
• EPA Substance Registry System: 4-(N,N-dimethylamino)-8-methoxy-2-phenylquinazoline(709030-49-9)

Safety Data

• Hazardous Substances Data: 709030-49-9(Hazardous Substances Data)

Upstream product

• 5395-00-6 N-(2-methoxyphenyl)benzamide 
• 90-04-0 2-methoxy-phenylamine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 172462-89-4 NU 1065 

Relevant articles and documents

The Synthesis of 8-Hydroxyquinazoline Derivatives and Their Acid-Base Interactions

The reaction of N-(2-R1-oxyphenyl)benzimidoyl chlorides with cyanamide derivatives in the presence of titanium tetrachloride as a catalyst has yielded some new 4-amino-8-R1-oxy-2-phenylquinazolines. pK a values have been determined for these compounds and the influence of substituents at the basicity of the parent system has been discussed. Some investigations on the methyl-quinazolinyl ether cleavage in different medium have been done yielding the appropriate hydroxyquinazoline derivatives. In those cases when the deprotection of 4-amino-8-methoxy-2-phenylquinazoline was carried in aqueous acidic solutions, the formation of the hydrolysis products 3,4-dihydro-2-phenyl-4-quinazolone derivatives was observed as well.