7094-34-0

Basic information

• Product Name: 3,3'-dichlorobenzophenone
• Synonyms: Benzophenone, 3,3'-dichloro-; Bis(3-chlorophenyl)methanone; Methanone, bis(3-chlorophenyl)-
• CAS NO: 7094-34-0
• Molecular Formula: C₁₃H₈Cl₂O
• Molecular Weight: 251.11
• Mol File: 7094-34-0.mol
• Article Data: 19

Chemical Properties

• Melting Point: 124°C
• Boiling Point: 356.37°C (rough estimate)
• Flash Point: 161.4°C
• Appearance: /
• Density: 1.2472 (rough estimate)
• Vapor Pressure: 5E-06mmHg at 25°C
• Refractive Index: 1.5555 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3,3'-dichlorobenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3'-dichlorobenzophenone(7094-34-0)
• EPA Substance Registry System: 3,3'-dichlorobenzophenone(7094-34-0)

Safety Data

• Hazardous Substances Data: 7094-34-0(Hazardous Substances Data)

Usage

General Description

3,3'-dichlorobenzophenone is a chemical compound with the molecular formula C13H8Cl2O. It is a white to pale yellow crystalline solid with a strong odor. 3,3'-dichlorobenzophenone is mainly used as an intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and dyes. It is also used as a photoinitiator in the production of polymer materials and as a UV absorber in a variety of plastic and rubber products. Additionally, this compound has been studied for its potential use in sunscreen formulations due to its ability to absorb UV radiation. However, 3,3'-dichlorobenzophenone is considered to be harmful if swallowed or inhaled, and may cause irritation to the skin and eyes. Therefore, proper safety precautions should be taken when handling this chemical.

InChI:InChI=1/C13H8Cl2O/c14-11-5-1-3-9(7-11)13(16)10-4-2-6-12(15)8-10/h1-8H

Upstream product

• 201230-82-2 carbon monoxide 
• 33756-91-1 tris(3-chlorophenyl)bismuthane 
• 64-18-6 formic acid 
• 625-99-0 3-iodochlorobenzene 
• 63503-60-6 3-chlorophenylboronic acid 
• 618-46-2 m-Chlorobenzoyl chloride 
• 587-04-2 m-Chlorobenzaldehyde 
• 79-37-8 oxalyl dichloride 
• 1248383-99-4 C₁₈H₁₂Cl₃In 
• 35190-07-9 1,2-bis(3-chlorophenyl)ethane-1,2-dione 
• 25077-87-6 3-chlorophenyllithium 
• 108-37-2 1-bromo-3-chlorobenzene 
• 541-41-3 chloroformic acid ethyl ester 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 144617-77-6 3,3-Bis-(3-chloro-phenyl)-3-hydroxy-propionitrile 
• 656806-83-6 bis(3-chlorophenyl)-dichloromethane 
• 10605-50-2 1,1-di(m-chlorophenyl)ethylene 
• 1037092-06-0 ethyl 5-(bis(3-chlorophenyl)(hydroxy)methyl)thiophene-2-carboxylate 
• 120553-11-9 3,3-bis(3-chlorophenyl)-2-propenal 
• 120553-40-4 (E)-5,5-bis(3-chlorophenyl)-2,4-pentadienoic acid 4-nitrophenyl ester 
• 120553-26-6 (E)-5,5-Bis-(3-chloro-phenyl)-penta-2,4-dienoic acid 
• 173200-57-2 3,3'-dichlorobenzhydryl chloride 

Relevant articles and documents

Method for preparing symmetric diarylketone through catalytic oxidative carbonylation

The invention discloses a method for preparing symmetric diarylketone of a formula (I) as shown in the description. The method comprises the following steps: mixing arylboronic acid (II) (Ar-B(OH)2 (II)), a palladium catalyst, a promoter and an organic solvent in a reactor, introducing air and CO having a volume ratio of (7-19):1, reacting under the conditions of a pressure of 1-6 atm and a temperature of 30-80 DEG C for 8-16 hours, and performing after-treatment on the reaction solution, thereby obtaining the product symmetric diarylketone. According to the method disclosed by the invention,the air directly serves as an oxidizing agent to replace the O2 to be applied to oxidative carbonylation of the arylboronic acid, and the ratio of the air to CO is beyond an explosion limit. Therefore, the catalytic system is safe and economic. The palladium catalyst is small in dosage and simple in separation and can be recycled for several times. The method disclosed by the invention is mild inreaction condition, excellent in substrate suitability and high in yield.

AZA-PYRIDONE COMPOUNDS AND USES THEREOF

Disclosed herein are aza-pyridone compounds, pharmaceutical compositions that include one or more aza-pyridone compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an orthomyxovirus infection, with an aza-pyridone compounds. Examples of an orthomyxovirus viral infection include an influenza infection.

Pd/Cu-cocatalyzed aerobic oxidative carbonylative homocoupling of arylboronic acids and CO: A highly selective approach to diaryl ketones

A highly selective Pd/Cu-cocatalyzed aerobic oxidative carbonylative homocoupling of arylboronic acids has been developed. This method employs a simple catalytic system, readily available boronic acids as the substrates, molecular oxygen as the oxidant, and 1 atm of CO/O2, which makes this method practical for further applications.