70997-30-7Relevant academic research and scientific papers
Reactions of N'-[2-Oxo-5-R-furan-3(2H)-ylidene]acylhydrazides with Primary and Secondary Alcohols
Igidov, N. M.,Ivanov, D. V.,Kiselev, M. A.,Kizimova, I. A.,Syutkina, A. I.
, p. 815 - 821 (2020/07/03)
Abstract: Reactions of primary and secondary alcohols with N'-[2-oxo-5-R-furan-3(2H)-ylidene]acylhydrazides resulted in the furan ring decylization toform 2-[2-(arylcarbonyl)hydrazinylidene]-4-alkyl esters of R-4-oxobutanoicacids.
TAUTOMERISM IN THE SERIES OF METHYL 5,5-DIMETHYL-2,4-DIOXOHEXANOATE ACYLHYDRAZONES
Yakimovich, S. I.,Nikolaev, V. N.,Zerova, I. V.
, p. 250 - 255 (2007/10/02)
It was shown by PMR spectroscopy that methyl 5,5-dimethyl-2,4-dioxohexanoate acylhydrazones exist in solutions as mixtures of the geometric isomers of the hydrazone and cyclic 5-hydroxypyrazoline forms.In the series of aroylhydrazones the introduction of electron-withdrawing substituents into the aromatic ring of the N-aroyl radical shifts the ring-chain equilibrium slightly toward the 5-hydroxypyrazoline tautomer.In the series of products from condensation with the hydrazides of aliphatic acids increase in the size of the substituents in the acyl part favors the open-chain hydrazone form.
TAUTOMERISM IN THE SERIES OF BENZOYLHYDRAZONES OF ALIPHATIC β-DICARBONYL COMPOUNDS
Yakimovich, S. I.,Nikolaev, V. N.,Blokhtina, S. A.
, p. 1247 - 1254 (2007/10/02)
It was shown by PMR spectroscopy that the benzoylhydrazones of aliphatic β-dicarbonyl compounds exist in solutions as tautomeric mixtures of the cyclic 5-hydroxypyrazoline and open forms.The latter are represented by the hydrazone or enehydrazine form or their combination, depending on the structure of the β-dicarbonyl component and the solvent.Increase in the size of the terminal substituent at the C=N bond displaces the equilibrium toward the cyclic 5-hydroxypyrazoline form, and the introduction of strong electron-withdrawing substituents at the C=N bond favors the hydrazone and cyclic forms.The benzoylhydrazones of symmetrical β-diketones have a cyclic 5-hydroxypyrazoline structure.
