71001-49-5

Upstream product

• 7062-95-5 potassium 2-cyanoacetate 
• 100-14-1 4-nitrobenzyl chloride 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 619-73-8 4-nitrobenzyl chloride 
• 372-09-8 cyanoacetic acid 
• 1071-36-9 sodium cyanoacetate 

Downstream Products

• 90765-82-5 Oximino-cyanessigsaeure-(4-nitro-benzylester) 
• 107124-41-4 ethyl p-nitrobenzyl 1,1-dithiomalonate 
• 107124-42-5 benzyl p-nitrobenzyl 1,1-dithiomalonate 
• 70388-95-3 Methylsulfanylthiocarbonyl-acetic acid 4-nitro-benzyl ester 
• 71001-46-2 [2-(2,2,2-Trichloro-ethoxycarbonylamino)-ethylsulfanylthiocarbonyl]-acetic acid 4-nitro-benzyl ester 
• 72888-51-8 [2-(4-Nitro-benzyloxycarbonylamino)-ethylsulfanylthiocarbonyl]-acetic acid 4-nitro-benzyl ester 
• 90947-48-1 Dinitro-cyanessigsaeure-(4-nitro-benzylester) 
• 77359-11-6 propanedioic acid mono[(4-nitrophenyl)methyl] ester 

Relevant academic research and scientific papers

Preparation method of nitrobenzyl hydrogen malonate

The invention relates to a preparation method of nitrobenzyl hydrogen malonate. Particularly, the preparation method comprises the steps of taking a compound shown as formula I and a compound shown asformula II as starting materials, performing esterification reaction to form an intermediate compound shown as formula III, and performing hydrolysis reaction on the compound shown as formula III toform nitrobenzyl hydrogen malonate (a compound shown as formula IV). The preparation method has the advantages of simplicity in operation, low cost, greenness, cleanness and the like and is suitable for industrial production.

Near infrared fluorescence probe for detection of Tau fibril for early diagnosis of Alzheimer's disease

The present invention provides a probe for detecting tau fiber protein, comprising a novel compound synthesized according to the present invention. The probe for detection of the present invention can effectively detect tau fiber protein, which is a major diagnostic target of Alzheimerandprime;s disease, thereby being able to be helpfully used for early diagnosis of the Alzheimerandprime;s disease.COPYRIGHT KIPO 2017