710307-06-5

Upstream product

• 151-50-8 potassium cyanide 
• 89675-44-5 (2S,4S,5R)-3,4-dimethyl-2,5-diphenyloxazolidine 
• 100-52-7 benzaldehyde 

Downstream Products

• 89675-44-5 (2S,4S,5R)-3,4-dimethyl-2,5-diphenyloxazolidine 
• 29843-11-6 (3R,5S,6R)-4,5-dimethyl-3,6-diphenylperhydro-1,4-oxazin-2-one 
• 710307-07-6 [((1S,2R)-2-Chloro-1-methyl-2-phenyl-ethyl)-methyl-amino]-phenyl-acetonitrile 

Relevant academic research and scientific papers

Expeditive synthesis of homochiral fused tri- and tetrazoles-piperazines from β-amino alcohols

N-Cyanomethyl and N-propargyl β-amino alcohols are chlorinated with SOCl2 and treated with NaN3 in DMSO. A substitution/cycloaddition process affords in good yields, with high diastereoselectivity and a regioselectivity depending on the substitution pattern of the starting amino alcohol, fused tri- and tetrazoles-piperazines. These heterocycles were further lithiated with n-BuLi at the benzylic position and reacted diastereoselectively with a range of electrophiles.

Synthesis, Structure and Reactions of Chiral Oxazinones Derived from L-Ephedrine

Optically pure 4,5-dimethyl-3,6-diphenylperhydro-1,4-oxazin-2-one 4 and 4,5-dimethyl-6-phenyl-3-(2-phenylvinyl)perhydro-1,4-oxazin-2-one 5 have been prepared by condensation of ephedrine, potassium cyanide and benzaldehyde or cinnamaldehyde.The lithium en