710350-72-4

Usage

Uses

2-Chloro-5-methoxycarbonylphenylboronic acid pinacol ester

Upstream product

• 365526-34-7 methyl 4-chloro-3-iodo-benzoate 
• 73183-34-3 bis(pinacol)diborane 
• 42860-04-8 4-chloro-3-iodobenzoic acid 
• 42860-10-6 3-bromo-4-chlorobenzoic acid 

Downstream Products

• 1070890-30-0 4-chloro-N-cyclopropyl-3-(3,5-dichloro-pyridin-2-yl)-N-(2-methoxy-phenyl)-benzamide 
• 1070890-31-1 4-chloro-3-(3,5-dichloro-pyridin-2-yl)-N-(2-hydroxy-phenyl)-N-methyl-benzamide 
• 1070892-47-5 4-chloro-3-(3,5-dichloro-pyridin-2-yl)-benzoic acid 
• 1070893-14-9 4-chloro-3-(3,5-dichloro-pyridin-2-yl)-benzoyl chloride 
• 1070892-46-4 4-chloro-3-(3,5-dichloro-pyridin-2-yl)-benzoic acid methyl ester 

Relevant academic research and scientific papers

HETEROCYCLIC INHIBITORS OF MONOCARBOXYLATE TRANSPORTERS

The invention provides compounds that inhibit monocarboxylate transporters, such as MCT1 and MCT4. Compounds of the invention can be used for treatment of a condition in a patient, wherein the condition is characterized by the heightened activity or by the high prevalence of MCT1 and/or MCT4, such as cancer or type II diabetes.

HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS AND COMBINATIONS THEREOF

Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS

Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.

GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO

GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure, wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.