71083-22-2Relevant academic research and scientific papers
A one-step synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid esters from o -nitrobenzaldehydes
Venkatesan, Hariharan,Hocutt, Frances M.,Jones, Todd K.,Rabinowitz, Michael H.
supporting information; experimental part, p. 3488 - 3491 (2010/08/03)
A straightforward and efficient one-step procedure for the synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters is described. The simple reductive cyclization is carried out by treating various substituted o-nitrobenzaldehydes with inex
Raf inhibitor compounds and methods of use thereof
-
Page/Page column 66, (2010/11/26)
Compounds of Formula I are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
