7112-00-7

Basic information

• Product Name: 2,4-dimethyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
• Synonyms: 3H-1,2,4-triazole-3-thione, 2,4-dihydro-2,4-dimethyl-5-phenyl-
• CAS NO: 7112-00-7
• Molecular Formula: C₁₀H₁₁N₃S
• Molecular Weight: 205.2794
• Mol File: 7112-00-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 274.6°C at 760 mmHg
• Flash Point: 119.8°C
• Density: 1.2g/cm³
• Vapor Pressure: 0.00537mmHg at 25°C
• Refractive Index: 1.643
• CAS DataBase Reference: 2,4-dimethyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dimethyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione(7112-00-7)
• EPA Substance Registry System: 2,4-dimethyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione(7112-00-7)

Safety Data

• Hazardous Substances Data: 7112-00-7(Hazardous Substances Data)

Usage

General Description

2,4-dimethyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione is a chemical compound with a triazole ring structure. It is classified as a thione, containing a sulfur atom bonded to a carbon atom. 2,4-dimethyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione is known for its potential pharmaceutical and biological activities, and has been studied for its anti-inflammatory, anticancer, and antimicrobial properties. It has also been investigated for its potential as a herbicide. The molecular structure and properties of 2,4-dimethyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione make it an interesting target for further research and development in the fields of medicine and agriculture.

Upstream product

• 98-88-4 benzoyl chloride 
• 6621-75-6 2,4-dimethylthiosemicarbazide 
• 1663-61-2 triethoxymethylbenzene 
• 100994-59-0 5-(2,5-difluorophenyl)-2,4-dimethyl-5-phenyl-1,2,4-triazolidine-3-thione 
• 100994-58-9 2,5-difluorobenzophenone 2,4-dimethylthiosemicarbazone 
• 7112-01-8 1-benzoyl-2,4-dimethylthiosemicarbazide 
• 4277-77-4 benzaldehyde-(2,4-dimethyl thiosemicarbazone) 
• 85068-36-6 2,5-difluorobenzophenone 
• 944-91-2 2,4-dimethyl-5-phenyl-2,4-dihydro-[1,2,4]triazol-3-one 

Relevant articles and documents

A Study of the Behaviour of 2,4-Substituted Thiosemicarbazides toward Orthoesters: Formation of Mesoionic Compounds

The reactions beetwen 2,4-disubstituted thiosemicarbazides and orthoesters in refluxing xylene led to the formation of the 1,2,4-triazoline-5-thione ring and to the 1,2,4-triazolium-5-thiolate ring. The formation of the mesoionic componds is due to rearrangement of the easily available 2,4-disubstituted thiosemicarbazides to 1,4-disubstituted thiosemicarbazides under the reaction conditions adopted. This method can be usefully used for the synthesis of mesoionic compounds, especially in the case of the 2-methyl-4-phenylthiosemicarbazide.

2,4-Dihydro-3H-1,2,4-triazole-3-thiones as Potential Antidepressant Agents

A series of 5-aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones was prepared and evaluated for potential antidepressant activity.Members of this series were generally prepared by the alkaline ring closures of the corresponding 1-aroylthiosemicarbazides.Several

The Bis(tricyclohexylstannyl) Sulfide Thionation of 3H-1,2,4-Triazol-3-ones

5-Aryl-2,4-dialkyl-2,4-dihydro-3H-1,2,4-triazol-3-ones may be converted in 55-74percent yield to the corresponding 3H-1,2,4-triazole-3-thiones by using the combination bis(tricyclohexylstannyl) sulfide/boron trichloride.