7112-02-9

Usage

Uses

Used in Personal Care Products:
N-(2-Hydroxyethyl)octanamide is used as a surfactant and emulsifying agent for its ability to reduce surface tension and enhance the solubilization of hydrophobic substances in water-based systems, making it a valuable ingredient in formulations for personal care products.
Used in Lubricants:
In the lubricant industry, N-(2-Hydroxyethyl)octanamide is utilized as a surfactant and emulsifying agent to improve the dispersion and stability of lubricating oils, ensuring efficient performance and reducing friction.
Used in Pharmaceuticals:
N-(2-Hydroxyethyl)octanamide is employed as a surfactant and emulsifying agent in pharmaceutical formulations to facilitate the dispersion of hydrophobic drug compounds in aqueous media, enhancing solubility and bioavailability.
Used in Antioxidant Applications:
Due to its antioxidant properties, N-(2-Hydroxyethyl)octanamide can be used to prevent oxidation in various industrial applications, protecting materials and products from degradation and extending their shelf life.
Used in Antibacterial Applications:
N-(2-Hydroxyethyl)octanamide's antibacterial properties make it suitable for use in applications where controlling bacterial growth is essential, such as in medical devices, water treatment, and food preservation.

Upstream product

• 124-07-2 Octanoic acid 
• 141-43-5 ethanolamine 
• 111-64-8 n-octanoic acid chloride 

Downstream Products

• 728007-10-1 C₄₀H₆₈N₂O₉ 
• 7596-88-5 N-dodecanoylglycine 
• 14246-55-0 N-myristoylglycine 
• 2441-41-0 N-palmitoyl glycine 
• 6333-54-6 N-stearoylglycine 
• 14305-32-9 N-n-decanoylglycine 
• 14246-53-8 N-(1-oxooctyl)glycine 

Relevant academic research and scientific papers

Antimicrobial Preservative Compositions for Personal Care Products

A personal product antimicrobial preservative composition for preservation of topical personal care formulations is provided and includes [A] one or more undecylenic acid derivatives depicted by Formula (I), [B] one or more octanoic acid derivatives depicted by Formula (II), and [C] 2-phenoxy ethanol or 2-ethyl hexyl glyceryl ether or mixture of these two ‘liquid alcohol ethers’; wherein, each of the two components [A] and [B] is present in the range of 5 to 20% by weight and together [A] and [B] constitute 10 to 30% by weight and the ‘liquid alcohol ether’, component [C], is present 70 to 90% by weight of the total preservative composition. A method for preserving personal care product from microbial attack is provided containing an aqueous phase comprising three component composition from about 0.5 to 2.5% by weight of the total personal care formulation.

ANTIMICROBIAL PRESERVATIVE COMPOSITIONS FOR PERSONAL CARE PRODUCTS

A personal product antimicrobial preservative composition for preservation of topical personal care formulations is provided comprising [A] one or more undecylenic acid derivatives depicted by Formula (I), [B] one or more octanoic acid derivatives depicted by Formula (II), and [C] 2-phenoxy ethanol or 2-ethyl hexyl glyceryl ether or mixture of these two ‘liquid alcohol ethers’; wherein, each of the two components [A] and [B] is present in the range of 5 to 20% by weight and together [A] and [B] constitute 10 to 30% by weight and the ‘liquid alcohol ether’, component [C], is present 70 to 90% by weight of the total preservative composition. A method for preserving personal care product from microbial attack is provided containing an aqueous phase comprising three component composition from about 0.5 to 2.5% by weight of the total personal care formulation.

ANTIMICROBIAL PRESERVATIVE COMPOSITIONS FOR PERSONAL CARE PRODUCTS

A personal product antimicrobial preservative composition for preservation of topical personal care formulations is provided comprising [A] one or more undecylenic acid derivatives depicted by Formula (I), [B] one or more octanoic acid derivatives depicted by Formula (II), and [C] 2-phenoxy ethanol or 2-ethyl hexyl glyceryl ether or mixture of these two 'liquid alcohol ethers'; wherein, each of the two components [A] and [B] is present in the range of 5 to 20 % by weight and together [A] and [B] constitute 10 to 30 % by weight and the 'liquid alcohol ether', component [C], is present 70 to 90 % by weight of the total preservative composition. A method for preserving personal care product from microbial attack is provided containing an aqueous phase comprising three component composition from about 0.5 to 2.5 % by weight of the total personal care formulation.

Synthesis and anticonvulsant activity of N-(2-hydroxyethyl)amide derivatives

A series novel of N-(2-hydroxyethyl)amide derivatives was synthesized and screened for their anticonvulsant activities by the maximal electroshock (MES) test, and their neurotoxicity was evaluated by the rotarod test (Tox). The maximal electroshock test showed that N-(2-hydroxyethyl)decanamide 1g, N-(2-hydroxyethyl)palmitamide 1l, and N-(2-hydroxyeth-yl)stearamide 1n were found to show a better anticonvulsant activity and also had lower toxicity than the marked anti-epileptic drug valproate. In the anti-MES potency test, these compounds exhibited median effective doses (ED50) of 22.0, 23.3, 20.5 mg/kg, respectively, and median toxicity doses (TD50) of 599.8, >1000, >1000 mg/kg, respectively, resulting in a protective index (PI) of 27.5, >42.9, >48.8, respectively. This is a much better protective index than that of the marked anti-epileptic drug valproate (PI = 1.6). To further investigate the effects of the anticonvulsant activity in several different models, compounds 1g, 1l, and 1n were tested having evoked convulsions with chemical substances, including pentylenetetrazloe, isoniazide, 3-mercaptopropionic acid, bicuculline, thiosemicarbazide, and strychnine.

USE OF CERTAIN N-ACYLETHANOLAMINES TO ACHIEVE ETHYLENE- AND CYTOKININ-LIKE EFFECTS IN PLANTS AND FUNGI

N-acylethanolamines (NAEs) that can deliver an ethylene- or cytokinin-like effects to a plant, plant part or fungus are disclosed. Also disclosed are methods of using the NAES.

Alternating (squaraine-receptor) sensory polymers: Modular one-pot synthesis and signal transduction via conformationally controlled exciton interaction

A novel class of nonconjugated polysquaraines consisting of isolated chromophores bridged by variable receptor linkers has been synthesized by a two-step one-pot procedure. Substantial reorganization of the polymer backbone conformation occurs upon external physical or chemical stimuli, leading to characteristic absorbance and emission signal responses both at long wavelengths, This novel approach to macromolecular sensor design in which signal transduction is based on backbone folding induced exciton interactions affords sensors with tunable selectivity.