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5-fluorodopamine is a synthetic chemical and a fluorinated analog of dopamine, a neurotransmitter crucial for movement and mood regulation. It is utilized in scientific research to investigate the impacts of Parkinson's disease and other neurological disorders.
Used in Scientific Research:
5-fluorodopamine is used as a research tool for studying the effects of Parkinson's disease and other neurological disorders due to its ability to selectively destroy dopamine-producing neurons in laboratory animals, enabling the examination of resulting motor and behavioral deficits.
Used in Pharmaceutical Development:
5-fluorodopamine is used as a potential treatment candidate for certain neurological conditions, given its interaction with the dopaminergic system and its effects on motor and behavioral functions.
Used in Neurodegenerative Disease Studies:
In the field of neurodegenerative disease research, 5-fluorodopamine is used as a means to induce Parkinson's-like symptoms in animal models, providing valuable insights into the disease's progression and potential therapeutic interventions.

71144-39-3

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71144-39-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 71144-39-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,1,4 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 71144-39:
(7*7)+(6*1)+(5*1)+(4*4)+(3*4)+(2*3)+(1*9)=103
103 % 10 = 3
So 71144-39-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H10FNO2.BrH/c9-6-4-8(12)7(11)3-5(6)1-2-10;/h3-4,11-12H,1-2,10H2;1H

71144-39-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-Fluorodopamine

1.2 Other means of identification

Product number -
Other names 6-fluorodopamin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71144-39-3 SDS

71144-39-3Downstream Products

71144-39-3Relevant academic research and scientific papers

Fast enzymatic synthesis of n.c.a. 6-[18F]fluorodopamine (FDA) from n.c.a. 6-[18F]FDOPA and the fate of 6-FDOPA and 6-FDA in neuroblastoma and Caki-1 cells after their uptake

Ku?i, Zyrafete,Ehrlichmann, Walter,Sauer, J?rg,Handgretinger, Rupert,Bruchelt, Gernot,Reischl, Gerald

, p. 438 - 447 (2019/07/18)

The catecholamine analogue [123I]mIBG has been used for scintigraphic imaging of neuroblastoma since 1984. It is taken up by the noradrenaline transporter (NAT), which is present in most neuroblastoma cells. An alternative imaging method could

Aromatic fluorination with xenon difluoride: L-3,4-dihydroxy-6-fluoro-phenylalanine

Firnau, Gunter,Chirakal, Raman,Sood, Sudesh,Garnett, Stephen

, p. 1449 - 1450 (2007/10/02)

L-3-Methoxy-4-hydroxyphenylalanine was fluorinated directly with XeF2 in CH2Cl2 at -60 deg C in vacuo.After hydrolysis with 48percent aqueous HBr, L-6-fluorodopa was obtained.The yield, based on XeF2, was 25percent.This reaction might be applied when chiral biomolecules are to be tagged with fluorine-18.

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