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Gamma-methoxy-4-methylbenzenebutenenitrile, also known as GMBN, is a versatile chemical compound belonging to the nitrile group, featuring a methoxy and methyl group on the benzene ring. It is widely utilized in organic synthesis and serves as an intermediate in the production of pharmaceuticals and agrochemicals. GMBN has garnered attention for its potential biological activities, such as anti-cancer and anti-inflammatory properties. Its ability to undergo various chemical reactions, including hydrolysis to form carboxylic acids and reduction to yield amines, further enhances its applicability in diverse chemical processes. Researchers in organic chemistry, pharmacology, and medicinal chemistry are particularly interested in GMBN due to its reactivity and potential biological applications.

71172-66-2

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71172-66-2 Usage

Uses

Used in Pharmaceutical Industry:
GMBN is used as an intermediate in the synthesis of various pharmaceuticals for its potential anti-cancer and anti-inflammatory properties. Its ability to participate in chemical reactions makes it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, GMBN is utilized as an intermediate in the production of various agrochemicals, contributing to its versatility in chemical processes and the development of effective products for agricultural applications.
Used in Organic Synthesis:
GMBN is employed as a key component in organic synthesis, where its reactivity and ability to undergo hydrolysis and reduction reactions allow for the creation of a wide range of chemical compounds for various applications.
Used in Research and Development:
GMBN is used as a subject of study in research and development within the fields of organic chemistry, pharmacology, and medicinal chemistry. Its potential biological activities and chemical properties make it an interesting candidate for exploring new applications and enhancing existing ones.

Check Digit Verification of cas no

The CAS Registry Mumber 71172-66-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,1,7 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 71172-66:
(7*7)+(6*1)+(5*1)+(4*7)+(3*2)+(2*6)+(1*6)=112
112 % 10 = 2
So 71172-66-2 is a valid CAS Registry Number.

71172-66-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-methoxy-4-(4-methylphenyl)butanenitrile

1.2 Other means of identification

Product number -
Other names EINECS 275-237-8

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71172-66-2 SDS

71172-66-2Downstream Products

71172-66-2Relevant academic research and scientific papers

Cu-Catalyzed Redox-Neutral Ring Cleavage of Cycloketone O-Acyl Oximes: Chemodivergent Access to Distal Oxygenated Nitriles

Ai, Wenying,Liu, Yaqian,Wang, Qian,Lu, Zhonglin,Liu, Qiang

, p. 409 - 412 (2018/01/27)

A chemodivergent copper-catalyzed ring opening of cycloketone oximes via radical-mediated C-C bond cleavage under redox-neutral conditions is described. This method allows the divergent synthesis of γ- and δ-acyloxylated, alkoxylated, and hydroxylated nitriles while avoiding the use of toxic cyanide reagents. Moreover, these reactions proceed under very mild conditions with good functional group tolerance. Notably, ring-opening reactions of the less-strained substrate cyclopentanone oxime also proceeded well under the established conditions.

Visible Light-Induced γ-Alkoxynitrile Synthesis via Three- Component Alkoxycyanomethylation of Alkenes

Yi, Hong,Zhang, Xu,Qin, Chu,Liao, Zhixiong,Liu, Jie,Lei, Aiwen

supporting information, p. 2873 - 2877 (2016/02/19)

A three-component alkoxycyanomethylation of alkenes is achieved using the iridium photoredox catalyst [fac-Ir(ppy)3]. This catalytic radical difunctionalization accomplishes both alkylation and alkoxylation of alkenes in one pot. Various alcohols can serve as the alkoxy sources in this transformation. In addition, the introduced cyano group can undergo further transformations into various useful functional groups.

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