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1-(5-chloro-1H-indol-3-yl)propan-2-amine is a chemical compound with the molecular formula C11H14ClN2. It is a derivative of indole, a heterocyclic aromatic organic compound, and features a chlorine atom at the 5-position of the indole ring. The compound has a propylamine chain attached to the 1-position of the indole, with the amine group located at the 2-position of the propane chain. This molecule is of interest in the field of medicinal chemistry, as it may exhibit biological activity and could be a potential precursor in the synthesis of pharmaceuticals or other bioactive compounds. Its specific applications and properties would depend on further research and development.

712-07-2

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712-07-2 Usage

Chemical class

Aromatic amine derivatives

Structural features

Indole ring with a chlorine atom at the 5-position
Propan-2-amine group attached to the indole ring

Potential applications

Pharmacological properties
Research and development in pharmaceuticals
Other applications in the scientific and medical communities

Interest

Subject of further investigation and exploration due to its chemical structure and properties

Functional groups

Aromatic indole ring
Chlorine atom
Aliphatic propan-2-amine group

Molecular weight

Approximately 211.68 g/mol (calculated from the molecular formula)

Physical state

Likely a solid at room temperature (based on the presence of an aromatic ring and amine group)

Solubility

Soluble in organic solvents like methanol, ethanol, and dimethyl sulfoxide (DMSO)
Insoluble in water (due to the presence of the aromatic ring and non-polar chlorine atom)

Stability

Stable under normal conditions
May be sensitive to light, heat, or moisture (due to the presence of the amine group)

Reactivity

Can undergo reactions typical of aromatic compounds, such as electrophilic substitution
The amine group can participate in reactions like acylation, alkylation, and reductive amination

Hazards

Potential irritant or toxic (due to the presence of an amine group)
Should be handled with care and proper safety precautions (gloves, eye protection, etc.)

Check Digit Verification of cas no

The CAS Registry Mumber 712-07-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,1 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 712-07:
(5*7)+(4*1)+(3*2)+(2*0)+(1*7)=52
52 % 10 = 2
So 712-07-2 is a valid CAS Registry Number.

712-07-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(5-chloro-1H-indol-3-yl)propan-2-amine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:712-07-2 SDS

712-07-2Downstream Products

712-07-2Relevant academic research and scientific papers

Alpha-ethyltryptamines as dual dopamine-serotonin releasers

Blough, Bruce E.,Landavazo, Antonio,Partilla, John S.,Decker, Ann M.,Page, Kevin M.,Baumann, Michael H.,Rothman, Richard B.

, p. 4754 - 4758 (2015/01/09)

The dopamine (DA), serotonin (5-HT), and norepinephrine (NE) transporter releasing activity and serotonin-2A (5-HT2A) receptor agonist activity of a series of substituted tryptamines are reported. Three compounds, 7b, (+)-7d and 7f, were found to be potent dual DA/5-HT releasers and were >10-fold less potent as NE releasers. Additionally, these compounds had different activity profiles at the 5-HT2Areceptor. The unique combination of dual DA/5-HT releasing activity and 5-HT2Areceptor activity suggests that these compounds could represent a new class of neurotransmitter releasers with therapeutic potential.

ORGANIC COMPOUNDS

-

Page/Page column 29, (2009/12/02)

The invention relates to organic compounds which have interesting pharmaceutical properties. In particular, the compounds are useful in the treatment and/or prevention of infections such as those caused by Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, Trypanosoma cruzi and parasites of the Leishmania genus such as, for example, Leishmania donovani. The invention also relates to pharmaceutical compositions containing the compounds, as well as processes for their preparation.

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