7122-91-0Relevant academic research and scientific papers
Fe2(CO)9-mediated [5+1] cycloaddition of vinylcyclopropanes and CO for the synthesis of α, β-cyclohexenones
Liu, Cheng-Hang,Zhuang, Zhe,Bose, Sritama,Yu, Zhi-Xiang
supporting information, p. 2752 - 2755 (2016/05/19)
A Fe2(CO)9-mediated [5+1] cycloaddition of vinylcyclopropanes (VCPs) and CO to α, β-cyclohexenones has been developed. The reaction can tolerate aryl and aliphatic groups at the α-position of VCPs, while VCP substrates with vinyl or alkynyl substitutions are not suitable ones. In addition, this reaction can also be used to synthesize bicyclic rings if an aryl group is attached to the vinyl moiety of the substrate. Compared to the Fe(CO)5-mediated [5+1] reaction, the use of cheap and safe Fe2(CO)9 and abandoning the photo-irradiation conditions are the two major advantages of the present method.
Synthesis of a sensitive and selective potassium-sensing fluoroionophore
Carpenter, Richard D.,Verkman
supporting information; experimental part, p. 1160 - 1163 (2010/05/18)
"Chemical Equation Presented" An efficient synthesis is reported that delivers in 5 steps and 52% overall yield a new structurally simplified fluorescent K+ sensor with improved K+ sensitivity and selectivity over existing K+ sensors. The synthesis procedure utilizes a new template-directed oxidative C-N bond-forming macrocyclization reaction and reports new approaches to Pd(O), Sandmeyer-like and metal-free aminoarylations, as well as organotitanium additions to vinylogous sulfonates.
1,4-Additions of the Highly Functionalized Copper Reagents RCu(CN)ZnI*2 BF3 to Trisubstituted Enones. A New BF3 Promoted Cyclization Reaction
Yeh, Ming Chang P.,Knochel, Paul,Butler, William M.,Berk, Scott C.
, p. 6693 - 6696 (2007/10/02)
The new copper reagents RCu(CN)ZnI*BF3 1 containing various functional groups like esters, cyanides, chlorides or enoates react with β,β'-disubstituted enones to afford the Michael adducts 4-7 in high yields (81-98percent).Cyano-substituted 1,4-adducts un
