71221-16-4

Upstream product

• 188290-36-0 thiophene 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 71221-21-1 5,10-bis-4-methoxyphenyl-15,20-diphenyl-21,23-dithiaporphyrin 
• 71221-25-5 5,10-bis-4-fluorophenyl-15,20-bis-4-methoxyphenyl-21,23-dithiaporphyrin 
• 71221-24-4 5,20-bis-(4-chlorophenyl)-10,15-bis(4-methoxyphenyl)-21,23-dithiaporphyrin 
• 71248-63-0 5,10,15,20-tetra-(p-methoxyphenyl)-21,23-dithiaporphyrin 
• 71221-23-3 1H,1'H-2,2'-[C,C'-bis-(4-methoxy-phenyl)-C,C'-thiophene-2,5-diylidene-dimethyl]-bis-pyrrole 
• 398514-79-9 2,5-bis[1-(4-methoxyphenyl)-1-pyrrolomethyl]thiophene 
• 22112-78-3 5,10,15,20-tetrakis(4-methoxyphenyl)porphyrin 

Relevant academic research and scientific papers

Core-modified porphyrins. Part 4: Steric effects on photophysical and biological properties in vitro

21,23-Dithiaporphyrins (2-10) were designed and prepared as analogues of 5,20-diphenyl-10,15-bis(4-carboxylatomethoxy)phenyl-21,23-dithiaporphyrin (1) to examine the impact of steric bulk at the 5- and 20-meso positions as well as the impact of symmetry.

Water soluble, core-modified porphyrins. 3. Synthesis, photophysical properties, and in vitro studies of photosensitization, uptake, and localization with carboxylic acid-substituted derivatives

Water soluble, core-modified porphyrins 1-5 bearing 1-4 carboxylic acid groups were prepared and evaluated in vitro as photosensitizers for photodynamic therapy. The 21,23-core-modified porphyrins 1-5 gave band I absorption maxima with λmax of

Water-soluble, core-modified porphyrins as novel, longer-wavelength-absorbing sensitizers for photodynamic therapy. II. Effects of core heteroatoms and meso-substituents on biological activity

Water-soluble, core-modified porphyrins were prepared and evaluated as sensitizers for photodynamic therapy (PDT). The addition of an aromatic aldehyde to 2,5-dilithiothiophene or -selenophene gave diol 3 as a nearly equimolar mixture of meso and d,1 dias