712275-17-7

Usage

Uses

Used in Pesticide Industry:
TBCB is used as a pesticidal agent for its ability to inhibit chitin biosynthesis in insects. This makes it a valuable tool for the development of novel pesticides to control insect populations.
Used in Pharmaceutical Research:
TBCB has been studied for its potential as an anti-cancer agent, as well as a treatment for parasitic infections. Its carbamate nature allows it to be a promising candidate for the development of new pharmaceuticals targeting various diseases.
Used in Organic Synthesis:
TBCB is also used in the field of organic synthesis, where it can be employed as a building block or intermediate in the synthesis of more complex organic compounds. This makes it a valuable tool for researchers working on the development of new organic materials and molecules.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 273399-95-4 (6-chloro-1H-benzo[d]imidazol-2-yl)methanamine 
• 95-83-0 4-Chloro-1,2-phenylenediamine 
• 4530-20-5 BOC-glycine 

Downstream Products

• 273399-95-4 (6-chloro-1H-benzo[d]imidazol-2-yl)methanamine 
• 1454584-91-8 C₂₃H₂₁ClFN₉ 

Relevant academic research and scientific papers

Synthesis and biological activity of squaramido-tethered bisbenzimidazoles as synthetic anion transporters

A series of squaramido-tethered bisbenzimidazoles were synthesized from the reaction of diethyl squarate with substituted 2-aminomethylbenzimidazoles. These conjugates exhibit moderate binding affinity toward chloride anions. They are able to facilitate the transmembrane transport of chloride anions most probably via an anion exchange process, and tend to be more active at acidic pH than at physiological pH. The viability of these conjugates toward four selected solid tumor cell lines was evaluated using an MTT assay and the results suggest that some of these conjugates exhibit moderate cytotoxicity probably in an apoptotic fashion.

Dibenzimidazole conjugates with pH dependent anion trans-membrane transport activity Synthesis method and synthesis method thereof (by machine translation)

13-bis-benzimidazole conjugate is synthesized by the method, the chloride ion transport activity of each conjugate under the acidic pH condition is higher than the activity at physiological pH, and the synthesized conjugate also shows moderate intensity toxicity on selected solid tumor cells. (by machine translation)

ANTI-INFECTIVE COMPOUNDS

The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.

THERAPEUTIC INHIBITORY COMPOUNDS

The invention provides compounds of Formula I and Formula II: A-B-C-D-E-F-G-J (I) C-D-E-F-G-J (II) wherein A, B, C, D, E, F, G, and J have any of the values defined in the specification, and salts thereof. The compounds are useful for inhibiting plasma kallikrein, and for treating a disease or condition in an animal where inhibition of plasma kallikrein is indicated.

Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties

The development of a series of potent and highly selective casein kinase 1δ/ε (CK1δ/ε) inhibitors is described. Starting from a purine scaffold inhibitor (SR-653234) identified by high throughput screening, we developed a series of potent and highly kinas

WEE1 DEGRADATION INHIBITORS

The invention provides compounds that inhibit the degradation of Weel. The compounds of the present invention are generally N-((1H-benzo[d]imidazol-2- yl)methyl)-9H-purin-6-amines. Compounds of the invention can be used for treatment of malconditions in p