71290-80-7Relevant academic research and scientific papers
Microwave-mediated derivatization of poly(styrene-co-allyl alcohol), a key step for the soluble polymer-assisted synthesis of heterocycles
Vanden Eynde, Jean Jacques,Rutot, Delphine
, p. 2687 - 2694 (1999)
Poly(styrene-co-allyl alcohol) can be readily esterified under classical conditions or under microwave irradiation. Some of the so-obtained polymers are effective precursors for the preparation of various nitrogen and oxygen heterocycles. The recycling of the polymeric auxiliary and its use in combinatorial chemistry are discussed.
ETUDE COMPARATIVE DE LA REACTIVITE DE L'ACETOACETATE D'ETHYLE ET DU 3-AMINOCROTONATE D'ETHYLE VIS-A-VIS DE COMPOSES PYRAZOLONIQUES
Maquestiau, A.,Haverbeke, Y. van,Eynde, J.-J. Vanden
, p. 451 - 458 (2007/10/02)
1-phenyl-3-methylpyrazolin-5-one, 1,5-dimethylpyrazolin-3-one and 1-phenyl-pyrazolidin-3,5-dione react with ethyl acetoacetate to yield pyrano pyrazole-6-ones.Starting from 1-phenyl-3-aminopyrazolin-5-one or from 1-methyl-5-aminopyrazolin-3-one, pyrazolo pyridin-6-ones are obtained.When ethyl 3-aminocrotonate instead of ethyl acetoacetate is used, the course of these reactions remains the same in most cases but yields are always higher.
