71292-45-0

Basic information

• Product Name: 1H-Pyrazol-4-ol, 1,5-dimethyl-3-phenyl-
• CAS NO: 71292-45-0
• Molecular Formula: C11H12N2O
• Molecular Weight: 188.229
• Mol File: 71292-45-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazol-4-ol, 1,5-dimethyl-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazol-4-ol, 1,5-dimethyl-3-phenyl-(71292-45-0)
• EPA Substance Registry System: 1H-Pyrazol-4-ol, 1,5-dimethyl-3-phenyl-(71292-45-0)

Safety Data

• Hazardous Substances Data: 71292-45-0(Hazardous Substances Data)

Upstream product

• 13466-29-0 benzaldehyde N-methyl hydrazone 
• 78-98-8 2-oxopropanal 

Relevant articles and documents

Reactions of Glyoxals with Hydrazones: A New Route to 4-Hydroxypyrazoles

N-Substituated hyrazones of aldehydes react with glyoxals under non-aqueous conditions to give N-substituted 4-hydroxypyrazoles; fourteen such products are described.In the presence of water, N-substituted 3-acyl-4-hydroxypyrazoles are produced from 2-oxoaldehyde hydrazones and glyoxals.It is shown that glyoxals combine in a 1:1 ratio with N-monosubstituted hydrazones to give 2-hydrazonoaldehydes as the kinetically controlled products.At room temperature or lower, these hydrazonoaldehydes rearrange to the more stable 2-oxoaldehyde hydrazones and react with glyoxals to give N-substituted 3-acyl-4-hydroxypyrazoles; sixteen such products are described.This synthesis, involving easily accessible starting materials, opens up a new, and for certain derivatives exclusive, route to 4-hydroxypyrazoles.