7133-32-6Relevant academic research and scientific papers
Pd-Catalyzed Regio- and Stereo-selective Carboxylation of Cycloalkanes with CO
Satoh, Ko-ichi,Watanabe, Jun,Takaki, Ken,Fujiwara, Yuzo
, p. 1433 - 1436 (2007/10/02)
The reactions of cycloalkanes with CO via the C-H bond activation by Pd(OAc)2 catalyst have been found to proceed regio- and stereo-selectively to give corresponding carboxylic acids.The reactivity of C-H bonds of cycloalkanes decreases in the order: tert- > sec- > prim-carbon, and the stereochemistry of the substitutents on the main products is all equatorial.
