713518-45-7

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 93-55-0 1-phenyl-propan-1-one 
• 13434-46-3 ethyl 2-cyano-3-phenylpent-2-enoate 
• 713518-42-4 ethyl 2-cyano-5-(dimethylamino)-4-methyl-3-phenylpenta-2,4-dienoate 

Downstream Products

• 183551-58-8 N-[3,5-bis(trifluoromethyl)benzyl]-2-chloro-N-[(2R)-3-hydroxy-2-methylpropyl]-5-methyl-4-phenylnicotinamide 
• 183551-56-6 N-[3,5-bis(trifluoromethyl)benzyl]-2-chloro-N-[(2S)-3-hydroxy-2-methylpropyl]-5-methyl-4-phenylnicotinamide 
• 183551-12-4 N-[3,5-bis(trifluoromethyl)benzyl]-2-chloro-N-(3-hydroxypropyl)-5-methyl-4-phenylnicotinamide 
• 183551-11-3 N-[3,5-bis(trifluoromethyl)benzyl]-2-chloro-N-(2-hydroxyethyl)-5-methyl-4-phenylnicotinamide 
• 183551-52-2 2-chloro-5-methyl-4-phenylnicotinic acid 

Relevant academic research and scientific papers

Amide-based atropisomers in tachykinin NK1-receptor antagonists: Synthesis and antagonistic activity of axially chiral N-benzylcarboxamide derivatives of 2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocin-6-one

A series of novel N-benzylcarboxamide derivatives of bicyclic compounds, 3,4-dihydropyrido[3,2-f][1,4]oxazepin-5(2H)-one and 2,3,4,5-tetrahydro-6H- pyrido[2,3-b][1,5]oxazocin-6-one, were synthesized by cyclization of N-benzyl-2-chloro-N-(2-hydroxyethyl)-