71381-91-4

Basic information

• Product Name: (+/-)-2-(4-isobutylphenyl)propanoyl chloride
• CAS NO: 71381-91-4
• Molecular Weight: 224.73
• Mol File: 71381-91-4.mol
• Article Data: 104

Chemical Properties

• CAS DataBase Reference: (+/-)-2-(4-isobutylphenyl)propanoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-2-(4-isobutylphenyl)propanoyl chloride(71381-91-4)
• EPA Substance Registry System: (+/-)-2-(4-isobutylphenyl)propanoyl chloride(71381-91-4)

Safety Data

• Hazardous Substances Data: 71381-91-4(Hazardous Substances Data)

Upstream product

• 31121-93-4 sodium 2-(4-isobutylphenyl)propionate 
• 79-37-8 oxalyl dichloride 
• 15687-27-1 ibuprofen 
• 38588-43-1 p-isobutylphenylacetic acid chloride 
• 1553-60-2 ibufenac 

Downstream Products

• 60576-98-9 2-(4-Isobutyl-phenyl)-propionic acid 2-dimethylamino-2-phenyl-ethyl ester 
• 60576-82-1 2-(4-Isobutyl-phenyl)-propionic acid 2-dimethylamino-2-phenyl-butyl ester 
• 64622-43-1 2-(4-Isobutyl-phenyl)-propionic acid 2-morpholin-4-yl-ethyl ester 
• 59512-25-3 N-2-(p-isobutylphenyl)propionylurea 
• 62394-52-9 2-(4-Isobutyl-phenyl)-propionic acid 2-(4-isobutyl-phenyl)-propyl ester 
• 206355-75-1 1-diazo-3-(4-isobutylphenyl)butan-2-one 
• 362470-66-4 (S)-1-carbamoylmethyl-4,4-dimethyl-2-oxopyrrolidinyl (S)-2-(4-isobutylphenyl)propionate 
• 15687-27-1 ibuprofen 
• 51146-56-6 (S)-ibuprofen 
• 51146-57-7 (R)-ibuprofene 
• 593279-83-5 2-[4-(2-methylpropyl)phenyl]-N-(pyridin-2-yl)propanamide 

Relevant articles and documents

Functionalization of α-C(sp3)?H Bonds in Amides Using Radical Translocating Arylating Groups

α-C?H arylation of N-alkylamides using 2-iodoarylsulfonyl radical translocating arylating (RTA) groups is reported. The method allows the construction of α-quaternary carbon centers in amides. Various mono- and disubstituted RTA-groups are applied to the arylation of primary, secondary, and tertiary α-C(sp3)?H-bonds. These radical transformations proceed in good to excellent yields and the cascades comprise a 1,6-hydrogen atom transfer, followed by a 1,4-aryl migration with subsequent SO2 extrusion.

Photoredox-Catalyzed Difunctionalization of Unactivated Olefins for Synthesizing Lactam-Substituted gem-Difluoroalkenes

Herein, the synthesis of lactam-substituted gem-difluoroalkenes has been developed through a photoredox-catalyzed radical cascade reaction. This developed photoredox-catalyzed, Br?nsted base-assisted intramolecular 5-exo-trig cyclization/intermolecular radical addition/β-fluoride elimination reaction offers a simple method for producing lactam, carbamate, or urea-substituted gem-difluoroalkenes with good functional group tolerance and high yields.

Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities

Two new series of ethyl benzoate bearing pyrrolizine and indolizine moieties 8–11 were synthesized and evaluated for their anti-inflammatory and anticancer activities. Among these derivatives, compounds 9a, 10b and 11b displayed in vivo anti-inflammatory