71434-61-2

Basic information

• Product Name: Benzenemethanol, 4-methyl-a-pentyl-
• CAS NO: 71434-61-2
• Molecular Formula: C13H20O
• Molecular Weight: 192.301
• Mol File: 71434-61-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 4-methyl-a-pentyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-methyl-a-pentyl-(71434-61-2)
• EPA Substance Registry System: Benzenemethanol, 4-methyl-a-pentyl-(71434-61-2)

Safety Data

• Hazardous Substances Data: 71434-61-2(Hazardous Substances Data)

Upstream product

• 110-53-2 1-Bromopentane 
• 104-87-0 4-methyl-benzaldehyde 
• 536-50-5 CH₃C₆H₄CH(CH₃)OH 
• 71-36-3 butan-1-ol 
• 66-25-1 hexanal 
• 4463-41-6 2-(p-tolyl)-1,3,2-dioxaborinane 

Downstream Products

• 1669-33-6 pentyl 4-methylphenyl ketone 

Relevant articles and documents

Tandem α-Alkylation/Asymmetric Transfer Hydrogenation of Acetophenones with Primary Alcohols

Tandem α-alkylation/asymmetric transfer hydrogenation of acetophenones with primary alcohols, mediated by a single ruthenium catalyst, is described. Under optimized reaction conditions and with use of [Ru(p-cymene)Cl2]2 in combination with an amino acid hydroxyamide ligand, the chiral secondary alcohol products were isolated in moderate yields and in moderate to good enantiomeric excess (up to 89 % ee). One catalyst - one pot - two reactions. Acetophenones are initially alkylated with primary alcohols by the borrowing hydrogen methodology. The alkylation products are directly converted to enantiomerically enriched secondary alcohols.

Direct β-alkylation of secondary alcohols with primary alcohols catalyzed by a Cp*Ir complex

(Chemical Equation Presented) A new catalytic system for β-alkylation of secondary alcohols has been developed. In the presence of [Cp*IrCl 2]2 (Cp* = pentamethylcyclopentadienyl) catalyst and base, the reactions of various secondary alcohols with primary alcohols give β-alkylated higher alcohols in good to excellent yields without any hydrogen acceptor or hydrogen donor. This reaction proceeds via successive hydrogen-transfer reactions and aldol condensation.