1669-33-6

Basic information

• Product Name: 1-p-tolylhexan-1-one
• Synonyms: 1-p-tolylhexan-1-one;pentyl 4-methylphenyl ketone
• CAS NO: 1669-33-6
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28142
• Mol File: 1669-33-6.mol
• Article Data: 19

Chemical Properties

• Melting Point: 39.5-40.5 °C(Solv: methanol (67-56-1))
• Boiling Point: 130-135 °C(Press: 4 Torr)
• Appearance: /
• Density: 0.936±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-p-tolylhexan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-p-tolylhexan-1-one(1669-33-6)
• EPA Substance Registry System: 1-p-tolylhexan-1-one(1669-33-6)

Safety Data

• Hazardous Substances Data: 1669-33-6(Hazardous Substances Data)

Usage

General Description

1-p-tolylhexan-1-one is an organic compound with the chemical formula C13H18O. It is a ketone with a unique aroma that is commonly used in the production of perfumes and other fragrance products. The compound is also used as a flavoring agent in food products. It is a colorless liquid with a molecular weight of 190.28 g/mol and a boiling point of 285°C. 1-p-tolylhexan-1-one is typically produced through organic synthesis methods and is considered to be relatively stable under normal conditions. It is important to handle this compound with care, as it can pose health and safety risks if not properly managed.

Upstream product

• 142-61-0 Hexanoyl chloride 
• 108-88-3 toluene 
• 1821-24-5 1-(p-methylphenyl)cyclohexanol 
• 6283-98-3 N-benzylhexanamide 
• 142-62-1 hexanoic acid 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 104-87-0 4-methyl-benzaldehyde 
• 1418228-44-0 diisopropyl 1-(4-(methyl)benzoyl)hydrazine-1,2-dicarboxylate 
• 693-25-4 n-pentylmagnesium bromide 
• 106-38-7 para-bromotoluene 
• 66-25-1 hexanal 
• 122-00-9 para-methylacetophenone 
• 71-36-3 butan-1-ol 
• 536-50-5 CH₃C₆H₄CH(CH₃)OH 

Downstream Products

• 740739-88-2 2-morpholin-4-ylmethyl-1-p-tolyl-hexan-1-one 
• 99-94-5 p-Toluic acid 
• 6976-74-5 pentyl 4-methylbenzoate 
• 78575-41-4 1-p-Tolyl-hexane-1,2-dione dioxime 
• 718588-26-2 2-Dimethylaminomethyl-1-p-tolyl-hexan-1-one 
• 135467-55-9 1-p-Tolyl-hexane-1,2-dione 2-oxime 

Relevant articles and documents

Iron-Catalyzed C-C Single-Bond Cleavage of Alcohols

An iron-catalyzed deconstruction/hydrogenation reaction of alcohols through C-C bond cleavage is developed through photocatalysis, to produce ketones or aldehydes as the products. Tertiary, secondary, and primary alcohols bearing a wide range of substituents are suitable substrates. Complex natural alcohols can also perform the transformation selectively. A investigation of the mechanism reveals a procedure that involves chlorine radical improved O-H homolysis, with the assistance of 2,4,6-collidine.

Phosphine-Free NNN-Manganese Complex Catalyzed α-Alkylation of Ketones with Primary Alcohols and Friedl?nder Quinoline Synthesis

Herein, we report a very simple and inexpensive catalytic system based on Earth's abundant transition metal manganese and on a bench-stable phosphine-free NNN-pincer ligand for an atom-efficient α-alkylations of ketones with primary alcohols via hydrogen-autotransfer C?C bond formation protocol. The precatalyst could be generated in situ and could be activated by using catalytic amount of base under milder conditions. A range of ketones were efficiently diversified with a broad range of primary alcohols in good to excellent isolated yields. Remarkably, this catalyst could also be employed for the synthesis of quinoline derivatives using 2-aminobenzyl alcohol as an alkylating agent. The later reaction is highly benign producing only hydrogen and water as byproducts. (Figure presented.).

RhCl(CO)(PPh3)2 catalyzed α-alkylation of ketones with alcohols

A simple and efficient method for α-alkylation of ketones with primary alcohols catalyzed by RhCl(CO)(PPh3)2 without additional additives under mild conditions is developed. It has a wide substrate scope, high atom-efficiency and chemoselectivity. It is an environmentally friendly method to build C[sbnd]C bond because water is the only byproduct.