7147-50-4

Usage

Chemical class

Thiourea derivatives

Physical state

White crystalline solid

Usage

Intermediate in organic synthesis

Potential application

Corrosion inhibitor for metals

Biological activity

Studied for its potential as an anti-tumor agent

Structure

Two 4-methoxyphenyl groups attached to a central thiourea moiety

Research interest

Subject of various studies due to its interesting and diverse properties

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 2231-57-4 Thiocarbohydrazide 

Downstream Products

• 119023-46-0 N¹,N⁵-di(2-p-methoxyphenyl-4-oxothiazolidine-3-yl)thiourea 
• 119023-40-4 3-{[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-amino}-2-{[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazono}-thiazolidin-4-one 
• 36951-42-5 2-(2-(4-methoxybenzylidene)hydrazinyl)thiazol-4(5H)-one 
• 347843-91-8 4-(4-methoxy-benzylideneamino)-5-(4-methoxyphenyl)-2H-1,2,4-triazole-3(4H)-thione 
• 1412457-77-2 (Z)-methyl 2-[(Z)-3-((E)-(4-methoxybenzylidene)amino)-2-((E)-(4-methoxybenzylidene)hydrazono)-4-oxothiazolidin-5-ylidene]acetate 

Relevant academic research and scientific papers

Synthesis and characterization of some dithiocarbohydrazones

Three bisthiocarbohydrazones had been synthesized and characterized. The structures of the three compounds were determined by elemental analysis, IR, MS, 1HNMR and 13CNMR. The crystal structure of one of the compounds was determined

Synthesis of thiocarbohydrazones and evaluation of their in vitro antileishmanial activity

Background: Leishmaniasis is a protozoan parasitic vector-borne disease which is endemic in 88 tropical countries. Infected sandfly is the main vector of this disease, while there are several other vectors, parasites, and reservoirs involved in the transm

Synthesis of novel triazoles, tetrazine, thiadiazoles and their biological activities

An expedient synthesis of novel triazoles, tetrazine and thiadiazoles, using conveniently accessible and commercially available starting materials has been achieved. The synthesized compounds were characterized by spectroscopic and elemental analyses, and screened for their antibacterial activities against four different strains, namely E. coli, P. aeruginosa, S. aureus and B. megaterium. In particular, the compounds 5, 24 and 26h exhibited excellent antibacterial activities compared to the reference antibiotic. To get further insight about their behavior, these compounds were tested for their antioxidant activities via SOD-like activity, DPPH free radical scavenging activity, ABST and NO, which showed promising results. Furthermore, these compounds effectively promoted the cleavage of genomic DNA as well, in the absence of any external additives.

Synthesis and Structure of Some Thiazole Derivatives

The addition of thiosemicarbazones 1 to α-halo acids 2 is shown to give 2-hydrazino-2-thiazolin-4-ones 3 and not 3-substituted 2-imino-3-(methyleneimino)thiazolidin-4-ones 4.The independent synthesis of 2-thiazolin-4-one derivatives 3 is also described.

Synthesis and Characterization of Bis-thiocarbonohydrazones

Several bis-thiocarbonohydrazones have been synthesized using improved methods.The compounds prepared have been characterized by elemental analyses, melting points, and IR and PMR spectra.