7148-59-6

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl (2E)-2-cyano-3-methyl-4-phenylbut-2-enoate is used as an intermediate for the synthesis of various compounds, particularly in the development of new medications. Its anti-inflammatory and analgesic properties make it a valuable ingredient in the creation of pharmaceutical products.
Used in Agrochemical Industry:
In the agrochemical industry, ethyl (2E)-2-cyano-3-methyl-4-phenylbut-2-enoate is also used as an intermediate for the synthesis of various compounds, contributing to the development of agrochemical products.
Used as a Flavoring Agent in Food and Beverages:
Ethyl (2E)-2-cyano-3-methyl-4-phenylbut-2-enoate is used as a flavoring agent in food and beverages, adding a fruity aroma and taste to various products. Its pleasant odor and solubility in organic solvents make it suitable for use in the food and beverage industry.

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 103-79-7 1-phenyl-acetone 

Downstream Products

• 5333-06-2 1-hydroxy-3-methyl-2-naphthonitrile 
• 20621-69-6 2-cyano-3-methyl-4-phenyl-butyric acid ethyl ester 
• 29840-37-7 α,β-Dicyan-β-benzyl-buttersaeureaethylester 
• 7315-68-6 3-methyl-4-phenylbutanoic acid 
• 14944-23-1 3-methyl-1-tetralone 
• 6279-96-5 3-methyl-3,4-diphenyl-butyric acid 
• 34599-63-8 2,3-dimethyl-4-phenylbutanoic acid 
• 854433-36-6 2-cyano-2,3-dimethyl-4-phenyl-butyric acid ethyl ester 
• 32980-47-5 2-benzyl-2-methyl-succinic acid 
• 91391-88-7 α-Methyl-α-benzyl-bernsteinsaeure-dinitril 
• 88613-45-0 α-Methyl-α-(4-nitro-benzyl)-bernsteinsaeure 
• 4815-38-7 ethyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate 

Relevant academic research and scientific papers

Substituted 2-Aminothiopen-derivatives: A potential new class of GluR6-Antagonists

In the course of search for new therapeutic agents against epilepsy new inhibitors for the kainate receptor subtypes GluR5 and GluR6 were synthesized. We were able to synthesize new substituted thieno[2,3-d]pyrimidines 3a,b, 4a,b, 5a,b as well as thiophene-3-carboxamides 2a-d and a multitude of substituted 4-methyl-5-phenylthiophene-3-carboxylic acids. All compounds described herein were tested for their antagonistic effect towards the kainate receptor subtypes GluR5 and GluR6. The highest activity was observed for ethyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate 1c with an IC50 = 0.75 μM at the GluR6 receptor.

Synthese de methoxycarbonylindenes, dihydro-1,2 naphtalenes et benzocycloheptene. Obtention des indanones-1, des tetralones-1 et de la benzosuberone correspondantes

The synthesis of methoxycarbonylindenes, 1,2-dihydro-naphtalenes, and benzocycloheptene starting from the corresponding 1-indanones, 1-tetralones, and benzosuberone is reported.The starting ketones were synthesized by methods described in the literature which were optimized; in some cases new processes are described.