7148-59-6 Usage
General Description
Ethyl (2E)-2-cyano-3-methyl-4-phenylbut-2-enoate, also known as ethyl 2-cyano-3-methyl-4-phenyl-2-butenate, is a chemical compound with the molecular formula C13H13NO2. It is commonly used as an intermediate in the pharmaceutical and agrochemical industries for the synthesis of various compounds. This chemical is a colorless to light yellow liquid with a fruity odor and is soluble in organic solvents. It is known for its ability to exhibit anti-inflammatory and analgesic properties, making it a valuable ingredient in the development of new medications. Additionally, ethyl (2E)-2-cyano-3-methyl-4-phenylbut-2-enoate is also used as a flavoring agent in food and beverages.
Check Digit Verification of cas no
The CAS Registry Mumber 7148-59-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,4 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7148-59:
(6*7)+(5*1)+(4*4)+(3*8)+(2*5)+(1*9)=106
106 % 10 = 6
So 7148-59-6 is a valid CAS Registry Number.
7148-59-6Relevant articles and documents
Substituted 2-Aminothiopen-derivatives: A potential new class of GluR6-Antagonists
Briel,Rybak,Kronbach,Unverferth
scheme or table, p. 69 - 77 (2010/03/24)
In the course of search for new therapeutic agents against epilepsy new inhibitors for the kainate receptor subtypes GluR5 and GluR6 were synthesized. We were able to synthesize new substituted thieno[2,3-d]pyrimidines 3a,b, 4a,b, 5a,b as well as thiophene-3-carboxamides 2a-d and a multitude of substituted 4-methyl-5-phenylthiophene-3-carboxylic acids. All compounds described herein were tested for their antagonistic effect towards the kainate receptor subtypes GluR5 and GluR6. The highest activity was observed for ethyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate 1c with an IC50 = 0.75 μM at the GluR6 receptor.
