71569-65-8Relevant academic research and scientific papers
New hydrazine and hydrazide quinoxaline 1,4-di-N-oxide derivatives: In silico ADMET, antiplasmodial and antileishmanial activity
Quiliano, Miguel,Pabón, Adriana,Ramirez-Calderon, Gustavo,Barea, Carlos,Deharo, Eric,Galiano, Silvia,Aldana, Ignacio
, p. 1820 - 1825 (2017)
We report the design (in silico ADMET criteria), synthesis, cytotoxicity studies (HepG-2 cells), and biological evaluation of 15 hydrazine/hydrazide quinoxaline 1,4-di-N-oxide derivatives against the 3D7 chloroquine sensitive strain and FCR-3 multidrug re
