71591-33-8Relevant academic research and scientific papers
Efficient synthesis of O-succinimidyl-(tert-butoxycarbonylamino)methyl carbamates derived from α-amino acids accelerated by ultrasound: Application to the synthesis of ureidodipeptides
Sureshbabu, Vommina V.,Sudarshan, Naremaddepalli S.,Kantharaju
, p. 2168 - 2184 (2008/09/21)
The synthesis of O-succinimidyl-(tert-butoxycarbonylamino)methyl carbamates employing isocyanates made through the Curtius rearrangement of Boc-amino acid azides in the presence of N-hydroxysuccinimide under the influence of ultrasound is described. Copyright Taylor & Francis Group, LLC.
Oral Bioavailability of a New Class of μ-Opioid Receptor Agonists Containing 3,6-Bis[Dmt-NH(CH2)n]-2(1H)-pyrazinone with Central-Mediated Analgesia
Jinsmaa, Yunden,Miyazaki, Anna,Fujita, Yoshio,Li, Tingyou,Fujisawa, Yutaka,Shiotani, Kimitaka,Tsuda, Yuko,Yokoi, Toshio,Ambo, Akihiro,Sasaki, Yusuke,Bryant, Sharon D.,Lazarus, Lawrence H.,Okada, Yoshio
, p. 2599 - 2610 (2007/10/03)
The inability of opioid peptides to be transported through epithelial membranes in the gastrointestinal tract and pass the blood-brain barrier limits their effectiveness for oral application in an antinociceptive treatment regime. To overcome this limitat
Chemical Synthesis of Fully Active and Heat-stable Fragments of Heat-stable Enterotoxin of Enterotoxigenic Escherichia coli Strain 18D
Yoshimura, Shoko,Takao, Toshifumi,Ikemura, Haruo,Aimoto, Saburo,Shimonishi, Yasutsugu,et al.
, p. 1381 - 1387 (2007/10/02)
Two shorter peptides of a heat-stable enterotoxin (STp), which is produced by enterotoxigenic Escherichia coli strain 18D, were prepared by two different procedures; i) chemical synthesis and ii) Edman-degradation of STp.These peptid
Synthesis and pharmacological activity of dermorphin tetrapeptide-analogs
Salvadori,Sarto,Tomatis
, p. 489 - 493 (2007/10/02)
The authors report on the synthesis and pharmacological activity of twenty-four tetrapeptide-analogs of the opioid heptapeptide dermorphin; their terminal amino group were replaced by guanidino functions and/or the C-termini were changed into amide moieti
