716358-34-8

Upstream product

• 158144-80-0 1-Boc-4-phenyl-4-piperidinecarbaldehyde 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 

Downstream Products

• 716358-36-0 (1-benzoyl-4-phenylpiperidine-4-yl)acetaldehyde 
• 716358-35-9 N-Boc-4-(2-oxoethyl)-4-phenyl-1-piperidine 

Relevant academic research and scientific papers

[2-(4-Phenyl-4-piperidinyl)ethyl]amine based CCR5 antagonists: derivatizations at the N-terminal of the piperidine ring

Several series of CCR5 antagonists have been discovered by derivatization at the N-terminal of the piperidine ring of the core template 2. Some derivatives exhibited potent inhibition against HIV-1infection. The pharmacokinetic properties of the lead comp

CCR5 ANTAGONISTS AS THERAPEUTIC AGENTS

The present invention relates to compounds of formula (I) or pharmaceutically acceptable derivatives thereof, useful in the treatment or prophylaxis of CCR5-related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).