71690-05-6

Basic information

• Product Name: 2,3-DICHLORO-5-FORMYLPYRIDINE
• Synonyms: 2,3-DICHLORO-5-FORMYLPYRIDINE;5,6-DICHLOROPYRIDINE-3-CARBALDEHYDE;5,6-Dichloropyridine-3-carboxaldehyde;5,6-Dichloro-3-pyridinecarboxaldehyde;5,6-Dichloropyridyl-3-carboxaldehyde
• CAS NO: 71690-05-6
• Molecular Formula: C₆H₃Cl₂NO
• Molecular Weight: 176
• Product Categories: Pyridine;Boronic Acid;Heterocycle-Pyridine series
• Mol File: 71690-05-6.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 268.604 °C at 760 mmHg
• Flash Point: 116.248 °C
• Appearance: /
• Density: 1.489 g/cm³
• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.608
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 2,3-DICHLORO-5-FORMYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DICHLORO-5-FORMYLPYRIDINE(71690-05-6)
• EPA Substance Registry System: 2,3-DICHLORO-5-FORMYLPYRIDINE(71690-05-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 71690-05-6(Hazardous Substances Data)

Usage

Uses

5,6-Dichloropyridyl-3-carboxaldehyde is used to prepare [(pyridyl)piperazinyl]benzimidazoles analogs as potent, orally available antagonists of the transient receptor potential vanilloid 1 and analgesics. It is also used to synthesize heterocyclic aryl isoxazolines with insecticidal activities.

InChI:InChI=1/C6H3Cl2NO/c7-5-1-4(3-10)2-9-6(5)8/h1-3H

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 162327-73-3 5,6-dichloro-N-methoxy-N-methyl-3-pyridinecarboxamide 
• 54127-30-9 5,6-dichloro-3-pyridinemethanol 
• 41667-95-2 5,6-dichloronicotinic acid 
• 54127-29-6 5,6-dichloronicotinoyl chloride 

Downstream Products

• 1073616-37-1 (S)-N-(4-chloro-3-trifluoromethylphenyl)-4-(3-chloro-5-(1,2-dihydroxyethyl)pyridin-2-yl)piperazine-1-carboxamide 
• 1073616-26-8 (S)-3-chloro-5-(1,2-dihydroxyethyl)-3',6'-dihydro-2'H-[2,4']bipyridinyl-1'-carboxylic acid (3-chloro-4-trifluoromethylphenyl)amide 
• 1073616-33-7 (S)-4-(3-chloro-5-(1,2-dihydroxyethyl)pyridin-2-yl)-N-(4-trifluoromethoxyphenyl)piperazine-1-carboxamide 
• 1073616-35-9 (S)-4-(3-chloro-5-(1,2-dihydroxyethyl)pyridin-2-yl)-N-(4-trifluoromethylphenyl)piperazine-1-carboxamide 
• 1073616-38-2 4-(3-chloro-5-(1,3-dihydroxypropan-2-yl)pyridin-2-yl)-N-(4-trifluoromethylphenyl)-5,6-dihydropyridine-1(2H)-carboxamide 
• 1073616-41-7 3-chloro-5-(methylsulfonamidomethyl)-N-[4-(trifluoromethyl)phenyl]-3',6'-dihydro-(2,4'-bipyridine)-1'(2'H)-carboxamide 
• 1073616-32-6 (S)-N-(4-tert-butylphenyl)-4-(3-chloro-5-(1,2-dihydroxyethyl)pyridin-2-yl)piperazine-1-carboxamide 
• 71690-06-7 2,3-dichloro-5-(difluoromethyl)pyridine 
• 1073617-14-7 (R)-3-chloro-5-(1,2-dihydroxyethyl)-N-[4-(trifluoromethyl)phenyl]-3',6'-dihydro-(2,4'-bipyridine)-1'(2'H)-carboxamide 
• 1073616-24-6 (S)-3-chloro-5-(1,2-dihydroxyethyl)-N-[4-(trifluoromethyl)phenyl]-3',6'-dihydro-(2,4'-bipyridine)-1'(2'H)-carboxamide 
• 943137-86-8 3-(5-chloro-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl)-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole 
• 950482-85-6 5-(3,5-dichlorophenyl)-3-(5,6-dichloro-3-pyridyl)-5-trifluoromethyl-4,5-dihydroisoxazole 
• 1308279-71-1 ethyl (E)-3-{2-[3'-(1-adamantyl)-4'-benzyloxyphenyl]-3-chloro-5-pyridinyl}-2-propenoate 
• 1308279-77-7 ethyl (E)-3-{2-[3'-(1-adamantyl)-4'-hydroxyphenyl]-3-chloro-5-pyridinyl}-2-propenoate 

Relevant articles and documents

A PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDINE COMPOUNDS AND INTERMEDIATES THEREOF

The present invention discloses a process for the preparation of substituted pyridine compounds of formula (I), comprises a step in which vinylogous nitriles of formula (II), are obtained from substituted α,β-unsaturated nitrile compounds of formula (III), and a further step of converting the vinylogous nitrile compounds of formula (II) into substituted pyridines of formula (I); wherein R1, R2, R3, R4 and LG are as defined in the description.

BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS

The present invention discloses compounds of Formula (I), or pharmaceuticall acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising th

HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES

The invention relates to aryl substituted heterocyclyl sulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.