717-01-1

Basic information

• Product Name: 3-HYDROXY-4-NITRO-BENZOIC ACID ETHYL ESTER
• Synonyms: 3-HYDROXY-4-NITRO-BENZOIC ACID ETHYL ESTER;RARECHEM AL BI 0673
• CAS NO: 717-01-1
• Molecular Formula: C₉H₉NO₅
• Molecular Weight: 211.17
• Mol File: 717-01-1.mol

Chemical Properties

• Melting Point: 84 °C
• Boiling Point: 355.8±27.0 °C(Predicted)
• Appearance: /
• Density: 1.370±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 6.11±0.13(Predicted)
• CAS DataBase Reference: 3-HYDROXY-4-NITRO-BENZOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-HYDROXY-4-NITRO-BENZOIC ACID ETHYL ESTER(717-01-1)
• EPA Substance Registry System: 3-HYDROXY-4-NITRO-BENZOIC ACID ETHYL ESTER(717-01-1)

Safety Data

• Hazardous Substances Data: 717-01-1(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
3-Hydroxy-4-nitro-benzoic acid ethyl ester is used as a reagent for the synthesis of 2H-1,4-benzoxazin-3(4H)-ones. It is involved in the reductive cyclization of 2-(2-nitrophenoxy)acetonitrile adducts in the presence of Fe/acetic acid. This process is essential for the production of various organic compounds with potential applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Hydroxy-4-nitro-benzoic acid ethyl ester may be utilized in the development of new drugs and pharmaceutical compounds. Its unique chemical structure allows it to participate in various chemical reactions, leading to the formation of bioactive molecules with potential therapeutic applications.
Used in Research and Development:
3-Hydroxy-4-nitro-benzoic acid ethyl ester is also used in research and development settings, where chemists and scientists explore its potential applications and reactions. 3-HYDROXY-4-NITRO-BENZOIC ACID ETHYL ESTER can be a valuable tool in understanding the mechanisms of chemical reactions and the synthesis of new organic compounds.

Upstream product

• 64-17-5 ethanol 
• 619-14-7 3-hydroxy-4-nitro-benzoic acid 

Downstream Products

• 86400-58-0 5-carbethoxy-2-nitro-phenyl triflate 
• 61394-49-8 ethyl 2-oxindoline-5-carboxylate 
• 86400-64-8 3-benzyl-5-chloromethyl-indolin-2-one 
• 86400-63-7 3-benzyl-5-hydroxymethyl-indolin-2-one 
• 86400-62-6 5-carboxy-3-benzyl-indolin-2-one 
• 86400-60-4 5-carbethoxy-3-benzylidene-indolin-2-one 
• 86400-61-5 5-carbethoxy-3-benzyl-indolin-2-one 
• 86400-59-1 diethyl 5-carbethoxy-2-nitro-benzyl malonate 
• 86400-65-9 3-acetoxy-3-benzyl-5-chloromethyl-7-nitro-indolin-2-one 
• 112249-82-8 methyl 5-bromo-2-(5-ethoxycarbonyl-2-nitrophenoxy)valerate 
• 72101-53-2 3-butoxy-4-nitrobenzoic acid 
• 5987-82-6 oxybuprocaine hydrochloride 

Relevant articles and documents

PIPERAZINE DERIVATIVES AS MAGL INHIBITORS

The invention provides new heterocyclic compounds having general Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, X, Y1 and Y2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.

BENZOIC ACID COMPOUNDS FOR REDUCING URIC ACID

Uric acid in mammalian subjects is reduced and excretion of uric acid is increased by administering a compound of Formula I. The uric acid-lowering effects of the compounds of this invention are used to treat or prevent a variety of conditions including g

SPIRO AZETIDINE ISOXAZOLE DERIVATIVES AND THEIR USE AS SSTR5 ANTAGONISTS

Provided is a compound represented by the following formula (1) or a salt thereof, which has an SSTR5 antagonistic action: wherein each symbol has the same definition as in the specification.

Synthesis and chiral discrimination of cyclic aromatic amides and the determination of their absolute configuration by TD-DFT calculations

Novel chiral cyclic molecules composed of aromatic triamides were constructed in modest yield from 4-N-(4′-methoxybenzyl)amino-3-decyloxybenzoic acid using dichlorotriphenylphosphorane, because of the preorganized component of the tertiary benzanilide moi

Toward a novel class of antithrombotic compounds with dual function. Discovery of 1,4-benzoxazin-3(4H)-one derivatives possessing thrombin inhibitory and fibrinogen receptor antagonistic activities

A novel class of potential antithrombotic compounds with moderate thrombin inhibitory and fibrinogen receptor antagonistic activity is described. Combination of anticoagulant and antiaggregatory activity in the same molecular entity is presented as a new

ANTITHROMBOTIC COMPOUNDS WITH DUAL FUNCTION

The present invention comprises compounds of the general formula (I) : and pharmaceutically acceptable salts thereof, wherein the substituents have in the description specified meaning. The compounds are used as antithrombotic agents possessing inhibitory