7170-01-6

Basic information

• Product Name: 3-METHYL-1H-1,2,4-TRIAZOLE
• Synonyms: 3(5)-Methyl-1,2,4-triazole;5-Methyl-1,2,4-triazole;3-METHYL-1H-1,2,4-TRIAZOLE;3-Methyl-1H-1,2,4-trizole;3-Methyl-4H-1,2,4-triazole;5-Methyl-1H-1,2,4-triazole;1H-1,2,4-triazole, 3-methyl-;3-methyl triazole
• CAS NO: 7170-01-6
• Molecular Formula: C₃H₅N₃
• Molecular Weight: 83.09
• EINECS: 1308068-626-2
• Product Categories: Heterocycle-other series;Heterocycle-Pyridine series
• Mol File: 7170-01-6.mol
• Article Data: 12

Chemical Properties

• Melting Point: 44-48°C
• Boiling Point: 233.1 °C at 760 mmHg
• Flash Point: 114.7 °C
• Appearance: /
• Density: 1.178 g/cm³
• Vapor Pressure: 0.0569mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: soluble in Methanol
• PKA: 10.60±0.20(Predicted)
• CAS DataBase Reference: 3-METHYL-1H-1,2,4-TRIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-1H-1,2,4-TRIAZOLE(7170-01-6)
• EPA Substance Registry System: 3-METHYL-1H-1,2,4-TRIAZOLE(7170-01-6)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-36/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 7170-01-6(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow powder

InChI:InChI=1/C3H5N3/c1-3-4-2-5-6-3/h2H,1H3,(H,4,5,6)

Upstream product

• 7271-44-5 2,3-dihydro-5-methyl-1,2,4-triazole-3(1H)-thione 
• 21532-07-0 3,4-diamino-5-methyl-1,2,4-triazole 
• 7271-44-5 3-methyl-5-mercapto-4H-1,2,4-triazole 
• 127237-67-6 3-Methyl-1-pyrrolidin-1-ylmethyl-1H-[1,2,4]triazole 
• 624-84-0 formic acid hydrazide 
• 20939-15-5 3-methyl-4-amino-5-mercapto-1,2,4-triazole 
• 62-55-5 thioacetamide 
• 79745-99-6 1-benzoyl-3-methyl-1,2,4-triazole 

Downstream Products

• 1001412-02-7 C₂₂H₂₃N₇O₃S 
• 1185019-89-9 1-(2-Fluoro-4-nitro-phenyl)-5-methyl-1H-[1,2,4]triazole 
• 1185019-82-2 1-(2-methoxy-4-nitrophenyl)-3-methyl-1H-1,2,4-triazole 
• 16759-48-1 3-methyl-1-(4-nitrophenyl)-1H-1,2,4-triazole 
• 1185190-19-5 4-(3,5-dimethylphenylsulfanyl)-3-iodo-6-methyl-5-(3-methyl-[1,2,4]triazol-1-ylmethyl)pyridin-2(1H)-one 
• 1185190-31-1 4-(3,5-dimethylphenylsulfanyl)-3-iodo-6-methyl-5-(5-methyl-[1,2,4]triazol-1-ylmethyl)pyridin-2(1H)-one 
• 1407831-40-6 (4R)-6-(4-chlorophenyl)-1,4-dimethyl-8-(5-methyl-1H-1,2,4-triazol-1-yl)-5,6-dihydro-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepine 
• 3213-91-0 3-phenyl-5-methyl-<1.2.4>triazole 
• 3213-94-3 5-(p-methylphenyl)-3-methyl-1H-1,2,4-triazole 
• 66492-63-5 5-(4-chlorophenyl)-3-methyl-1H-1,2,4-triazole 
• 1407831-43-9 (4R)-6-(4-chlorophenyl)-1,4-dimethyl-8-(3-methyl-1H-1,2,4-triazol-1-yl)-5,6-dihydro-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepine 
• 1417340-09-0 C₂₄H₂₃N₇O₃ 
• 1055909-21-1 C₂₄H₂₃N₇O₃ 
• 1356009-23-8 1-(2-(4-methoxybenzyloxy)-4-nitrophenyl)-3-methyl-1H-1,2,4-triazole 

Relevant articles and documents

Seco C-nucleoside analogs of the 1,2,4-triazole

The seco C-nucleosides 3-(1,2,3,4,5-penta-O-acetyl-D-gluco- and D-galacto-pentitol-1-yl)-1H-1,2,4-triazoles (6 and 7) were obtained in one pot by deamination and dethiolation of 4-amino-3-(D-gluco- and D-galacto-pentitol-1-yl)-5-mercapto-1,2,4-triazoles (

The synthesis of nebularine and its analogs via oxidative desulfuration in aqueous nitric acid

The synthesis of nebularine and its analogs has been achieved via oxidative desulfuration in H2O for the first time. With 50% HNO3as an oxidant and solvent, 18 products were obtained in good yields (70%–94%). The oxidative desulfuration system could tolerate different functional groups including fluoro, chloro, amino, alkyl, allyl, ribosyl, deoxyribosyl, and arabinofuranosyl groups.More importantly, the drug nebularine could be obtained successfully on a 20 g scale, which made this route more attractive for industrial applications.

Process for preparing triazole substituted azaindoleoxoacetic piperazine derivatives and novel salt forms produced therein

A process is provided for preparing triazole substituted azaindoleoxoacetic piperazine derivative. Novel intermediates produced in the above process, and novel N-1 and amorphous forms of a 1,2,3-triazole substituted azaindoloxoacetic piperazine derivatives and processes for producing such novel forms are also provided.