71780-43-3

Upstream product

• 5372-81-6 dimethyl aminoterephthalate 
• 42934-01-0 2,5-Bis(hydroxymethyl)phenol 
• 55045-01-7 2-Acetoxyterephthalsaeure-dimethylester 
• 6342-72-9 dimethyl hydroxyterephthalate 
• 71780-42-2 3-Hydroxy-4-hydroxymethyl-3,4-O-isopropylidenbenzylalkohol 

Relevant academic research and scientific papers

Vitamin D analogues

The invention concerns novel bi-aromatic compounds having the formula: which are analogs of vitamin D, the process of preparing them, as well as their use in pharmaceutical compositions in human or veterinary medicine, particularly in dermatology, cancer treatment, treatment of auto-immune diseases, and in organ or tissue transplants. Cosmetic compositions and methods of use are also included.

Nonproteinogenic Amino Acids, IV. - EPC Synthesis of L-(+)-Forphenicine

Enantiomerically pure L-(+)-forphenicine (12) is synthesized starting from purchasable 3-methoxybenzaldehyde (1) by the use of (4S,5S)-(+)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane (2) as a chiral auxiliary and prussic acid. 12 is identical with the natural product which has been isolated from the culture broth of an Actinomyces species and which is known to be a potent inhibitor of alkaline phosphatase.