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Z-L-Phe-OCH(CF3)2, also known as N-benzyloxycarbonyl-L-phenylalanine difluoromethyl ketone, is a synthetic peptide derivative. It is a protected amino acid, where the L-phenylalanine (L-Phe) is modified with a benzyloxycarbonyl (Z) group and a difluoromethyl ketone (CF3)2 group. The Z group is a common protecting group used in peptide synthesis to prevent unwanted side reactions, while the difluoromethyl ketone group is a unique modification that can influence the reactivity and properties of the molecule. Z-L-Phe-OCH(CF3)2 is used in the synthesis of peptides and other bioactive molecules, where the protection and modification of the amino acid side chain are crucial for achieving the desired product.

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  • 71785-36-9 Structure
  • Basic information

    1. Product Name: Z-L-Phe-OCH(CF3)2
    2. Synonyms: Z-L-Phe-OCH(CF3)2
    3. CAS NO:71785-36-9
    4. Molecular Formula:
    5. Molecular Weight: 449.35
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 71785-36-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Z-L-Phe-OCH(CF3)2(CAS DataBase Reference)
    10. NIST Chemistry Reference: Z-L-Phe-OCH(CF3)2(71785-36-9)
    11. EPA Substance Registry System: Z-L-Phe-OCH(CF3)2(71785-36-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 71785-36-9(Hazardous Substances Data)

71785-36-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 71785-36-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,7,8 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 71785-36:
(7*7)+(6*1)+(5*7)+(4*8)+(3*5)+(2*3)+(1*6)=149
149 % 10 = 9
So 71785-36-9 is a valid CAS Registry Number.

71785-36-9Relevant articles and documents

α-chymotrypsin-catalysed peptide synthesis via the kinetically controlled approach using activated esters as acyl donors in organic solvents with low water content: Incorporation of non-protein amino acids into peptides

Miyazawa, Toshifumi,Nakajo, Shin'ichi,Nishikawa, Miyako,Hamahara, Kazumi,Imagawa, Kiwamu,Ensatsu, Eiichi,Yanagihara, Ryoji,Yamada, Takashi

, p. 82 - 86 (2007/10/03)

The α-chymotrypsin-catalyzed peptide synthesis via the kinetically controlled approach using activated esters as acyl donors in orgnanic solvents with low water content was presented. The methyl esters of N-Z derivatives of racemic non-protein amino acids were chosen as carboxy components. They allowed the peptide-bond formation and optical resolution simultaneously to yield homochiral peptides. This method is useful for the incorporation of non-protein amino acids into peptides.

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