71785-92-7Relevant academic research and scientific papers
Synthesis and in vitro biological evaluation of carbonyl group-containing analogues for σ1 receptors
Wang, Wei,Cui, Jinquan,Lu, Xiaoxia,Padakanti, Prashanth K.,Xu, Jinbin,Parsons, Stanley M.,Luedtke, Robert R.,Rath, Nigam P.,Tu, Zhude
experimental part, p. 5362 - 5372 (2011/10/02)
To identify the ligands for σ1 receptors that are potent and selective, analogues of prezamicol and trozamicol scaffolds of carbonyl-containing vesicular acetylcholine transporter (VAChT) inhibitors were explored. Of the 23 analogues synthesize
Nonsymmetrical bipiperidyls as inhibitors of vesicular acetylcholine storage
Efange,Khare,Parsons,Bau,Metzenthin
, p. 985 - 989 (2007/10/02)
Introduction of a nitrogen atom into the cyclohexane ring of 2-(4- phenylpiperidinyl)cyclohexanol (vesamicol, AH5183) yielded two positional isomers, 5-azavesamicol (5, prezamicol) and 4-azavesamicol (6, trozamicol). As inhibitors of vesicular acetylcholi
