71814-52-3

Basic information

• Product Name: 3,5-dimethyl-1-phenyl-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one
• Synonyms: 4H-pyrazolo[4,3-c]quinolin-4-one, 1,5-dihydro-3,5-dimethyl-1-phenyl-
• CAS NO: 71814-52-3
• Molecular Formula: C₁₈H₁₅N₃O
• Molecular Weight: 289.3312
• Mol File: 71814-52-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 515.3°C at 760 mmHg
• Flash Point: 265.4°C
• Density: 1.25g/cm³
• Vapor Pressure: 1E-10mmHg at 25°C
• Refractive Index: 1.677
• CAS DataBase Reference: 3,5-dimethyl-1-phenyl-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dimethyl-1-phenyl-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one(71814-52-3)
• EPA Substance Registry System: 3,5-dimethyl-1-phenyl-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one(71814-52-3)

Safety Data

• Hazardous Substances Data: 71814-52-3(Hazardous Substances Data)

Upstream product

• 97789-05-4 1-phenyl-3-methyl-4,5-dihydro-1H-pyrazolo<4,5-c>quinolin-4-one 
• 74-88-4 methyl iodide 
• 956111-57-2 3-acetyl-4-methoxy-1-methylquinolin-2(1H)-one 
• 59-88-1 phenylhydrazine hydrochloride 
• 54289-76-8 3-acetyl-4-hydroxy-1-methyl-2(1H)-quinolone 
• 100-63-0 phenylhydrazine 
• 1046810-18-7 C₁₈H₁₆ClN₃O 
• 685891-37-6 1-methyl-2-oxo-3-[1-(phenylhydrazono)ethyl]-1,2-dihydroquinolin-4-yl 4-methylbenzenesulfonate 
• 93873-16-6 4-hydroxy-1-methyl-3-[1-(2-phenylhydrazinylidene)ethyl]quinolin-2(1H)-one 

Relevant articles and documents

Synthesis and antioxidant properties of some novel 1,3,4,2-oxadiazaphosphepino[6,7-c]quinolinones and pyrazolo[3,4:4′,3′]quinolino[5,1-c][1,4,2]oxazaphosphinine

A series of novel 1,3,4,2-oxadiazaphosphepino[6,7-c]quinolinones 3–5, 9, and 11 have been synthesized from treatment of 4-hydroxy-1-methyl-3-[1-(2-phenylhydrazinylidene)ethyl]quinolin-2(1H)-one (2) with some phosphorus sulfides, diethyl phosphite and phen

Object-oriented synthetic approach toward angular and linear fused pyrazoloquinolines of biological importance with InCl3 catalyst

A simple and short approach for the synthesis of pyrazolo[3,4-b]quinoline (3a-3p) and pyrazolo[4,3-c]quinoline (6a-6 h) using various Lewis acid catalysts was developed. InCl3 was found to be more effective in providing greater yield of product

Regioselective synthesis of 2,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-ones by the cyclization of 3-acyl-4-methoxy-1-methylquinolinones with hydrazines

Reaction of 3-acyl-4-methoxy-1-methylquinolinones 2 and 5 with hydrazines has been investigated under different experimental conditions. Compound 2 always gave rise selectively and exclusively to the regioisomeric 1,3-disubstituted- or 2,3-disubstituted-pyrazolo[4,3-c]quinolin-4(5H)one (compounds 3a,b or 4a,b, respectively), while reaction of 5 with N-methylhydrazine led to a mixture of pyrazoles 7a and 8a. With N-phenylhydrazine, compounds 7b or 8b were regioselectively obtained. Compound 8a could be selectively synthesized working in solventless conditions. Structural elucidation of all products was independently achieved by NMR spectroscopy.