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(E)-2-(2-hydroxystyryl)-3-phenylquinazolin-4(3H)-one is a complex organic compound belonging to the quinazolinone class, characterized by a quinazolinone core with a 2-hydroxystyryl group at position 2 and a phenyl group at position 3. This molecule exhibits a specific geometric isomerism (E) due to the presence of a double bond in the styryl moiety. It is known for its potential applications in medicinal chemistry, particularly as a precursor or building block for the synthesis of various bioactive compounds. The compound's structure and properties make it a subject of interest for researchers exploring new therapeutic agents and pharmaceuticals.

71814-95-4

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71814-95-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 71814-95-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,8,1 and 4 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 71814-95:
(7*7)+(6*1)+(5*8)+(4*1)+(3*4)+(2*9)+(1*5)=134
134 % 10 = 4
So 71814-95-4 is a valid CAS Registry Number.

71814-95-4Downstream Products

71814-95-4Relevant academic research and scientific papers

Synthesis, photochemical and luminescent properties of ortho-hydroxystyrylquinazolinone-linked benzocrown ethers

Ovchinnikova, Irina G.,Kim, Grigory A.,Matochkina, Eugene G.,Kodess, Mikhail I.,Slepukhin, Pavel A.,Kovalev, Igor S.,Nosova, Emilia V.,Rusinov, Gennady L.,Charushin, Valery N.

, p. 16 - 28 (2017/10/17)

Photoinduced transformations of (E)-2-(2-hydroxystyryl)quinazolinone-linked benzo[15(18)]crown-5(6) ethers in solutions have been studied by using UV–vis absorption and NMR spectroscopy. These crown ethers were found to have dual emission at 520 and 650 nm, associated with proton-transfer tautomer emission (ESIPT-luminescence) as a rare case of excited-state proton-transfer reaction in the non-pseudocyclic chromophoric systems. It was established also, that the organic bases affect the luminescence intensity of solutions of these compounds in the 550–650-nm wavelength range. An X-ray crystallography analysis of molecular structures of crown ethers and their complexes in crystals has been carried out. The fact of reversible photo/thermal E-Z isomerization in DMF and Et3N for these macroheterocyclic compounds has been confirmed. An opportunity to control the photochemical isomerization rate of quinazolinone 2-(hydroxyphenyl)ethenyl derivatives by changing pH of the medium has been demonstrated.

Synthesis, photochemical and luminescent properties of (E)-2-(2-hydroxyarylethylene)-3-phenylquinazolin-4(3H)-ones

Ovchinnikova,Kim,Matochkina,Kodess,Barykin,E?tsov,Nosova,Rusinov,Charushin

, p. 2467 - 2477 (2015/08/03)

Photoinduced transformations of 2-styrylquinazolinones in solutions were studied using absorption and NMR spectroscopy methods. A possibility of control of the photochemical isomerization rate of quinazolinone 2-(hydroxyaryl)ethenyl derivatives by changin

Compounds for modulating TRPV3 function

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Page/Page column 47, (2010/11/28)

The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.

Condensation of 2-Methyl-3,1-benzoxazin-4-one with Schiff Bases: Simultaneous Introduction of Arylidene and Amine Moieties

Kumar, Pradeep,Mukerjee, Arya K.

, p. 24 - 26 (2007/10/02)

2-Methyl-3,1-benzoxazin-4-one (3), generated by cyclising N-acetylanthranilic acid with ethyl chloroformate in benzene containing triethylamine, reacts with schiff bases in situ when heated under reflux in gl. acetic acid to give 3-substituted 2-styryl-3,4-dihydro-4-quinazolones (7).

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