71856-54-7 Usage
Uses
Used in Pharmaceutical Industry:
5-amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile is used as a potential candidate for the development of new pharmaceuticals due to its unique structural features and the possibility of exhibiting important biological activities. Its electron-rich and electron-withdrawing groups may contribute to its potential as a therapeutic agent.
Used in Agrochemical Development:
In the agrochemical industry, 5-amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile may be utilized for the creation of new agrochemicals, given its potential biological activities and the need for innovative compounds in this field.
Further Investigation:
5-amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile requires additional experimental studies and research to evaluate its specific properties, functions, and potential uses in both the pharmaceutical and agrochemical industries. This will help determine its applicability and effectiveness in various therapeutic or chemical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 71856-54-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,8,5 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 71856-54:
(7*7)+(6*1)+(5*8)+(4*5)+(3*6)+(2*5)+(1*4)=147
147 % 10 = 7
So 71856-54-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H7BrN4/c11-8-3-1-2-4-9(8)15-10(13)7(5-12)6-14-15/h1-4,6H,13H2
71856-54-7Relevant academic research and scientific papers
Synthesis and adenosine receptor affinity of a series of pyrazolo[3,4-d]pyrimidine analogues of 1-methylisoguanosine
Harden,Quinn,Scammells
, p. 2892 - 2898 (2007/10/02)
Pyrazolo[3,4-d]pyrimidines are pyrazolo analogues of purines. They have been shown to be a general class of compounds which exhibit A1 adenosine receptor affinity. Two series of pyrazolo[3,4-d]pyrimidine analogues of 1-methylisoguanosine have been synthesized. The first involved substitution of the N1-position while the second involved substitution of the N5-position. Both alkyl and aryl substituents were examined. All compounds were tested for A1 adenosine receptor affinity by using a (R)-[3H]-N6-(phenylisopropyl)adenosine binding assay. The 3-chlorophenyl group showed the greatest activity in the N1-position and the butyl group produced the greatest activity in the N5-position. Combination of the best substituent in each of these positions enhanced the overall activity. The most potent compound was 4-amino-5-N-butyl-1-(3-chlorophenyl)-1H-pyrazolo[3,4-d] pyrimidin-6(5H)-one with an IC50 of 6.4 X 10-6 M. Selectivity at the receptor subclasses was examined by performing an A2 adenosine receptor affinity assay with [3H]CGS 21680. This series of compounds were slightly less potent at A2 receptors. 4-Amino-5-N-butyl-1-(3-chlorophenyl)-1H-pyrazolo[3,4-d] pyrimidin-6(5H)-one was the most potent compound with an IC50 of 19.2 X 10-6 M.
