5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile

Base Information

Chemical Name:5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile
CAS No.:71856-54-7
Molecular Formula:C10H7BrN4
Molecular Weight:263.10
Hs Code.:2933199090
DSSTox Substance ID:DTXSID30500583
Wikidata:Q72438826
Mol file:71856-54-7.mol

Synonyms:71856-54-7;5-AMINO-1-(2-BROMOPHENYL)-1H-PYRAZOLE-4-CARBONITRILE;5-amino-1-(2-bromophenyl)pyrazole-4-carbonitrile;MFCD03407394;SCHEMBL839068;DTXSID30500583;WCA85654;AKOS009564890;DS-12264;SY117296;A9386;CS-0060462;FT-0746567

Suppliers and Price of 5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
5-amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile 95%
1g
$ 204.00

Chemenu
5-amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile 95%
5g
$ 561.00

Ambeed
5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile 95+%
10g
$ 225.00

Ambeed
5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile 95+%
5g
$ 134.00

Ambeed
5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile 95+%
1g
$ 37.00

Ambeed
5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile 95+%
250mg
$ 15.00

Alichem
5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile
1g
$ 200.00

Alichem
5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile
5g
$ 612.00

AK Scientific
5-amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile
10g
$ 1527.20

Absolute Chiral
5-amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile 95%
250 mg
$ 298.00

Total 12 raw suppliers

Chemical Property of 5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:131°C
Refractive Index:1.712
Boiling Point:453.217 °C at 760 mmHg
Flash Point:227.898 °C
PSA：67.63000
Density:1.663 g/cm³
LogP:2.66988
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:261.98541
Heavy Atom Count:15
Complexity:274

Purity/Quality:

97% ^*data from raw suppliers

5-amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)N2C(=C(C=N2)C#N)N)Br

Technology Process of 5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile

There total 4 articles about 5-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 123-06-8
Ethoxymethylenemalononitrile

: 16732-66-4
2-bromophenylhydrazine

: 71856-54-7
5-amino-1-(2-bromo-phenyl)-1H-pyrazole-4-carbonitrile

Guidance literature:: In ethanol; for 1h; Heating;
DOI:10.1021/jm00113a031

Reference yield:

: 615-36-1
2-bromoaniline

: 71856-54-7
5-amino-1-(2-bromo-phenyl)-1H-pyrazole-4-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaNO₂, HCl, 2.) SnCl₂, HCl / 1.) H₂O, 0 deg C, 2.) H₂O, RT, 1 h

2: ethanol / Heating

With hydrogenchloride; tin(ll) chloride; sodium nitrite; In ethanol;
DOI:10.1021/jm00113a031