71864-40-9

Upstream product

• 186581-53-3 diazomethane 
• 71864-34-1 (tert-Butoxycarbonylamino-phenyl-methyl)-phosphonic acid 
• 35657-34-2 (O-pivaloylhydroxyl)amine 
• 16965-72-3 dimethyl α-diazobenzylphosphonate 
• 36198-87-5 dimethyl trimethylsilyl phosphite 
• 150884-50-7 benzaldehyde N-boc imine 
• 868-85-9 Dimethyl phosphite 

Downstream Products

• 110470-33-2 dimethyl α-aminobenzyl phosphonate 

Relevant academic research and scientific papers

Hydrophosphonylation of aldimines under catalysts-free conditions

Trimethylsilyl phosphite reacted with aldimines efficiently under catalysts-free conditions, giving α-aminophosphonates in good to excellent yields. Furthermore, the reaction can be scaled-up easily and the high yield can be maintained. Copyright

Nucleophilic carbene-mediated hydrophosphonylation of aldimines

Aldimines undergo efficient hydrophosphonylation reactions with dimethyl phosphite in the presence of nucleophilic heterocyclic- carbenes (NHCs) as organocatalysts to give the corresponding (α-aminoalkyl)phosphonates in moderate-to-excellent yields. Georg

Highly efficient synthesis of functionalized tertiary alcohols catalyzed by potassium alkoxide-crown ether complexes

A highly efficient Mukaiyama aldol reaction between ketones and trimethylsilyl enolates in the presence of potassium alkoxide-crown ether complexes as Lewis base catalysts (0.3-5 mol %), which minimized the competing retro-aldol reaction, was developed. T

N-H insertion reactions of rhodium carbenoids. Part 1. Preparation of α-amino acid and α-aminophosphonic acid derivatives

Rhodium(II) acetate-catalysed decomposition of diazophenylacetates 1 and 3 in the presence of a range of N-H compounds results in an N-H insertion reaction of the intermediate carbenoids and formation of N-substituted phenylglycine derivatives 2 and 4. The corresponding reactions of dimethyl α-diazobenzylphosphonate 5 constitute a simple route to aminophosphonates 6.