71868-15-0Relevant articles and documents
Preparation method for alpha-hydroxy ketone bifunctional photoinitiator
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Paragraph 0018-0030, (2020/06/02)
The invention provides a preparation method for an alpha-hydroxy ketone bifunctional photoinitiator. The preparation method comprises the following steps: with 4,4'-diisobutyryl diphenyl ether as a raw material, allowing the 4,4'-diisobutyryl diphenyl ether to react with chlorine, and carrying out hydrolyzing, crystallizing and purifying so as to obtain a product. The preparation method provided by the invention is high in yield, good in product appearance and low in cost, and has advantages in industrial production. In the step of a chlorination reaction, side reactions are effectively controlled; and in the step of hydrolysis, the problem of difficult layering of a water phase and an organic phase generated by using phase transfer catalysis and phase transfer catalysis is avoided.
Highly efficient C-H hydroxylation of carbonyl compounds with oxygen under mild conditions
Liang, Yu-Feng,Jiao, Ning
, p. 548 - 552 (2014/01/23)
A transition-metal-free Cs2CO3-catalyzed α-hydroxylation of carbonyl compounds with O2 as the oxygen source is described. This reaction provides an efficient approach to tertiary α-hydroxycarbonyl compounds, which are highly valued chemicals and widely used in the chemical and pharmaceutical industry. The simple conditions and the use of molecular oxygen as both the oxidant and the oxygen source make this protocol very environmentally friendly and practical. This transformation is highly efficient and highly selective for tertiary C(sp3)-H bond cleavage. OH, so simple! A transition-metal-free Cs2CO 3-catalyzed α-hydroxylation of carbonyl compounds with O 2 provided a variety of tertiary α-hydroxycarbonyl compounds (see scheme; DMSO=dimethyl sulfoxide), which are widely used in the chemical and pharmaceutical industry. The simple conditions and the use of molecular oxygen as both the oxidant and the oxygen source make this protocol very efficient and practical.
PROCESS FOR THE PREPARATION OF AROMATIC ALPHA-HYDROXY KETONES
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Page/Page column 16, (2010/01/29)
Process for the preparation of aromatic alpha-hydroxyketones (aromatic α- hydroxyketones) that does not require the use of chlorine, sulfuryl chloride or bromine and comprises the halogenation of an intermediate aromatic ketone with a hydrogen halide in the presence of an oxidising compound.