719267-77-3

Upstream product

• 1072-98-6 5-chloro-2-pyridylamine 
• 917926-26-2 ethyl 2-{[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]thio}-4-nitrobenzoate 
• 372198-66-8 4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-1,3-thiazole-2-thiol 
• 30493-40-4 1-(6-chloroimidazo[1,2-a]pyridin-3-yl)ethan-1-one 
• 751472-60-3 (2-{[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]thio}-4-nitrophenyl)methanol 

Relevant academic research and scientific papers

Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110α inhibitors

3-{1-[(4-Fluorophenyl)sulfonyl]-1H-pyrazol-3-yl}-2-methylimidazo[1,2-a]pyridine, 2a, was discovered in our chemical library as a novel p110α inhibitor with an IC50 of 0.67 μM, through screening in a scintillation proximity assay. Optimization o