30493-40-4

Basic information

• Product Name: 1-(6-chloroH-iMidazo[1,2-a]pyridin-3-yl)ethanone
• Synonyms: 1-(6-chloroH-iMidazo[1,2-a]pyridin-3-yl)ethanone;Ethanone, 1-(6-chloroiMidazo[1,2-a]pyridin-3-yl)-;1-(6-chloroimidazo[1,2-a]pyridin-3-yl)ethanone
• CAS NO: 30493-40-4
• Molecular Formula: C₉H₇ClN₂O
• Molecular Weight: 198.60638
• Mol File: 30493-40-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(6-chloroH-iMidazo[1,2-a]pyridin-3-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-chloroH-iMidazo[1,2-a]pyridin-3-yl)ethanone(30493-40-4)
• EPA Substance Registry System: 1-(6-chloroH-iMidazo[1,2-a]pyridin-3-yl)ethanone(30493-40-4)

Safety Data

• Hazardous Substances Data: 30493-40-4(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic compound

Structure

Contains a pyridine ring fused to an imidazole ring

Additional functional group

Ketone group attached to the pyridine ring

Presence of a substituent

Chloro substituent on the pyridine ring

Relevance in the field

Medicinal chemistry and pharmaceutical research

Potential

Possesses potential biological activity

Application

Utilized in the development of new drugs

Influence of chloro substituent

Adds to its reactivity and can influence its pharmacological properties

Versatility

Ketone functional group allows for further chemical modifications

Purpose of modifications

To enhance biological activity and selectivity

Upstream product

• 1072-98-6 5-chloro-2-pyridylamine 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 598-31-2 1-bromoacetone 

Downstream Products

• 719267-77-3 (2-{[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]sulfinyl}-4-nitrophenyl)methanol 
• 751472-60-3 (2-{[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]thio}-4-nitrophenyl)methanol 
• 917926-26-2 ethyl 2-{[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]thio}-4-nitrobenzoate 
• 372198-16-8 6-chloro-3-{2-[(2-methyl-5-nitrophenyl)thio]-1,3-thiazol-4-yl}imidazo[1,2-a]pyridine 

Relevant articles and documents

DERIVATIVES OF 4-(IMIDAZO[L,2-A]PYRIDIN-3-YL)-N-(PYRIDINYL)PYRIMIDIN- 2-AMINE AS THERAPEUTIC AGENTS

A novel class of heteroaryl compounds for use in the prevention and/or treatment of proliferative diseases and conditions including cancers. The compounds are considered to be capable of inhibiting cell proliferation by inhibiting the activity of FLT3 and its mutant forms and/or other protein kinases such as CDKs. The compounds have the general structure I:

A 2-amino-thiazole compounds (by machine translation)

The present invention relates to the technical field of pharmaceutical chemistry, particularly relates to a 2-amino thiazole compound or its pharmaceutically acceptable salts, its preparation method, and pharmaceutical compositions containing such compounds and its application in the preparation of antineoplastic. (by machine translation)