7193-94-4Relevant academic research and scientific papers
A simple method for the reduction of Schiff bases using biosynthesized nickel oxide nanoparticles
Muthuvinothini, Alagesan,Stella, Selvaraj
, p. 267 - 271 (2020/07/07)
An innovative and simple approach for the reduction of aldimines to the corresponding secondary amines was described using biosynthesized nickel oxide nanoparticles as heterogeneous catalyst and ammonium formate as the hydrogen donor. This catalytic trans
Screening of simple carbohydrates as a renewable organocatalyst for the efficient construction of 1,3-benzoxazine scaffold
Y?ld?r?m, Ayhan,Kaya, Yunus,G?ker, Mustafa
, (2021/10/12)
A convenient protocol for the two component preparation of 1,3-benzoxazines by using several protected and unprotected carbohydrate molecules as organocatalysts have been developed which is broadly applicable to condensation reaction between variety of Ma
Metal-Free Diaryl Etherification of Tertiary Amines by Ortho-C(sp2)-H Functionalization for Synthesis of Dibenzoxazepines and -ones
Jamsheena, Vellekkatt,Mahesha, Chikkagundagal K.,Joy, M. Nibin,Lankalapalli, Ravi S.
supporting information, p. 6614 - 6617 (2017/12/26)
A phenyliodine(III) diacetate mediated umpolung reactivity of the tertiary amines with suitably substituted o-hydroxybenzyl and phenyl groups is exploited to facilitate o-C(sp2)-H functionalization to afford diaryl ethers. The presence of an o-
Influence of substituent on equilibrium of benzoxazine synthesis from Mannich base and formaldehyde
Deng, Yuyuan,Zhang, Qin,Zhou, Qianhao,Zhang, Chengxi,Zhu, Rongqi,Gu, Yi
, p. 18341 - 18348 (2014/09/30)
N-Substituted aminomethylphenol (Mannich base) and 3,4-dihydro-2H-3- substituted 1,3-benzoxazine (benzoxazine) were synthesized from substituted phenol (p-cresol, phenol, p-chlorophenol), substituted aniline (p-toluidine, aniline, p-chloroaniline) and formaldehyde to study influence of substituent on equilibrium of benzoxazine synthesis from Mannich base and formaldehyde. 1H-NMR and charges of nitrogen and oxygen atoms illustrate effect of substituent on reactivity of Mannich base, while oxazine ring stability is characterized by differential scanning calorimetry (DSC) and C-O bond order. Equilibrium constants were tested from 50 °C to 80 °C, and the results show that substituent attached to phenol or aniline has same impact on reactivity of Mannich base; however, it has opposite influence on oxazine ring stability and equilibrium constant. Compared with the phenol-aniline system, electron-donating methyl on phenol or aniline increases the charge of nitrogen and oxygen atoms in Mannich base. When the methyl group is located at para position of phenol, oxazine ring stability increases, and the equilibrium constant climbs, whereas when the methyl group is located at the para position of aniline, oxazine ring stability decreases, the benzoxazine hydrolysis tends to happen and equilibrium constant is significantly low. the Partner Organisations 2014.
A quick route for the synthesis of 3-Aryl-3,4-dihydro-2H-benz[e]-1,3- oxazin-2-ones
Shukla, Davender Kumar,Rani, Manju,Khan, Arif Ali
, p. 4537 - 4540 (2013/06/27)
N-(2-Hydroxy)-benzyl-arylamines (1) gave substantially pure 3-aryl-3,4-dihydro-2H-benz[e]-1,3-oxazin-2-one 2 on cyclization with carbonyldiimidazole in DMSO in 20-30 min at 20-25 °C in excellent yields.
Synthesis and biological activity of some 3-aryl-3,4-dihydro-2h-benz[e]-1, 3-oxazines/6-bromo-3-aryl-3,4-dihydro-2h-benz[e]-1,3-oxazines
Shukla, Davender Kumar,Rani, Manju,Khan, Arif Ali,Tiwari, Kavita,Gupta, Rajinder K.
, p. 5921 - 5924 (2013/07/26)
N-(2-Hydroxy)-benzyl-arylamine (1) gives substantially pure 3-aryl-3,4-dihydro-2H-benz[e]-1,3-oxazines/6-bromo-3-aryl-3,4-dihydro-2H-benz[e] -1,3-oxazines (2) on cyclization with formaldehyde in methanol within 0.5-1.0 h at 65-68 C in excellent yields. Th
Efficient synthesis of 2,3-disubstituted-1,3-benzoxazines by chlorotrimethylsilane-mediated aza-acetalizations of aromatic aldehydes
Tang, Zilong,Zhu, Zhonghua,Yan, Lin,Chang, Shuhong,Liu, Hanwen
, p. 1116 - 1120 (2013/10/21)
A series of novel substituted 3,4-dihydro-2H-1,3-benzoxazines were prepared in moderate to good yields by aza-acetalizations of aromatic aldehydes with 2-(N-substituted aminomethyl)phenols in the presence of chlorotrimethylsilane or SnCl4. It w
SnCl4-catalyzed aza-acetalization of aromatic aldehydes: Synthesis of aryl substituted 3,4-dihydro-2H-1,3-benzoxazines
Tang, Zilong,Chen, Weiwen,Zhu, Zhonghua,Liu, Hanwen
, p. 1372 - 1383 (2012/04/04)
Stannic tetrachloride was an efficient Lewis acid catalyst for the aza-acetalization of aromatic aldehydes with o-arylaminomethyl phenols, and a series of novel aryl substituted 3,4-dihydro-2H-1,3-benzoxazines were prepared in good yields under mild condi
Synthesis and fungicidal activity of novel 2,3-disubstituted-1,3- benzoxazines
Tang, Zilong,Zhu, Zhonghua,Xia, Zanwen,Liu, Hanwen,Chen, Jinwen,Xiao, Wenjing,Ou, Xiaoming
, p. 8174 - 8185 (2012/09/25)
A series of new 2,3-disubstituted-3,4-dihydro-2H-1,3-benzoxazines were prepared in moderate to excellent yields by aza-acetalizations of aromatic aldehydes with 2-(N-substituted aminomethyl)phenols in the presence of TMSCl. Their structures were confirmed
