719306-97-5Relevant academic research and scientific papers
New piperidine scaffolds via nucleophilic reactivity of (-)-phenyloxazolopiperidine
Poupon, Erwan,Francois, David,Kunesch, Nicole,Husson, Henri-Philippe
, p. 3836 - 3841 (2007/10/03)
The present work illustrates the power of compound 2 as a chiral, nonracemic, and stable 2-piperideine (enamine) equivalent in the rapid and efficient construction of 3-substituted piperidines (carbon-carbon and carbon-sulfur bonds) such as 3-spiropiperidines. This methodology offers a new route to such systems that could compete with previously reported strategies.
