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FMOC-MET-ONP is a chemical compound that consists of three main components: FMOC, MET, and ONP. FMOC, or 9-fluorenylmethoxycarbonyl, serves as a protecting group in peptide synthesis, safeguarding the amine group of amino acids. MET, or methionine, is an essential amino acid present in proteins and plays a role in various biological functions. ONP, or o-nitrophenol, is a widely used chromogenic substrate in enzymatic assays, especially for detecting phosphatases. The combination of these components makes FMOC-MET-ONP a valuable tool in peptide chemistry and enzymatic assays, positioning it as a significant chemical in the fields of biochemistry and biomedical research.

71989-29-2

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71989-29-2 Usage

Uses

Used in Peptide Synthesis:
FMOC-MET-ONP is used as a protecting group in peptide synthesis for the amine group of amino acids. This application is crucial for preventing unwanted side reactions during the synthesis process, ensuring the correct formation of peptide bonds and the desired peptide sequence.
Used in Enzymatic Assays:
FMOC-MET-ONP is used as a chromogenic substrate in enzymatic assays, particularly for the detection of phosphatase enzymes. FMOC-MET-ONP's ability to change color upon enzymatic action allows for the monitoring of enzyme activity, providing a convenient and sensitive method for assessing enzyme function and inhibition.
Used in Biochemistry and Biomedical Research:
FMOC-MET-ONP is used as a research tool in biochemistry and biomedical research for studying the synthesis and function of peptides, as well as the activity of enzymes involved in various biological processes. Its multifaceted role in these fields highlights its importance in advancing scientific understanding and developing new therapeutic strategies.

Check Digit Verification of cas no

The CAS Registry Mumber 71989-29-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,9,8 and 9 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 71989-29:
(7*7)+(6*1)+(5*9)+(4*8)+(3*9)+(2*2)+(1*9)=172
172 % 10 = 2
So 71989-29-2 is a valid CAS Registry Number.
InChI:InChI=1/C26H24N2O6S/c1-35-15-14-24(25(29)34-18-12-10-17(11-13-18)28(31)32)27-26(30)33-16-23-21-8-4-2-6-19(21)20-7-3-5-9-22(20)23/h2-13,23-24H,14-16H2,1H3,(H,27,30)

71989-29-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name FMOC-MET-ONP

1.2 Other means of identification

Product number -
Other names FMOC-L-METHIONINE 4-NITROPHENYL ESTER

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71989-29-2 SDS

71989-29-2Downstream Products

71989-29-2Relevant academic research and scientific papers

Active Esters of 9-Fluorenylmethyloxycarbonyl Amino Acids and Their Application in the Stepwise Lengthening of a Peptide Chain

Bodanszky, Agnes,Bodanszky, Miklos,Chandramouli, Nagarajan,Kwei, Joseph Z.,Martinez, Jean,Tolle, John C.

, p. 72 - 76 (2007/10/02)

Preparation and properties of p-nitrophenyl esters of several 9-fluorenylmethyloxycarbonyl (Fmoc) amino acids are described.The Fmoc derivatives of the hindered amino acids valine and isoleucine were converted to the more reactive o-nitrophenyl esters whi

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