72002-30-3 Usage
General Description
D-6-oxo-pipecolinic acid, also known as D-6-APA, is a naturally occurring chemical compound that is a derivative of L-lysine. It is a key intermediate in the biosynthesis of the essential amino acid L-pipecolic acid, which plays a crucial role in the plant defense system against pathogens and is also involved in the metabolism of neurotransmitters in the human brain. D-6-oxo-pipecolinic acid has been studied for its potential therapeutic applications, including as an anti-inflammatory agent and for its neuroprotective properties. It is also being investigated for its role in immune regulation and its potential as a diagnostic marker for certain diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 72002-30-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,0,0 and 2 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 72002-30:
(7*7)+(6*2)+(5*0)+(4*0)+(3*2)+(2*3)+(1*0)=73
73 % 10 = 3
So 72002-30-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H9NO3/c8-5-3-1-2-4(7-5)6(9)10/h4H,1-3H2,(H,7,8)(H,9,10)/t4-/m1/s1
72002-30-3Relevant articles and documents
Lactams as prostanoid receptor ligands. Part 4: 2-Piperidones as selective EP4 receptor agonists
Elworthy, Todd R.,Brill, Emma R.,Caires, Christopher C.,Kim, Woongki,Lach, Leang K.,Tracy, Jahari Laurant,Chiou, San-San
, p. 2523 - 2526 (2007/10/03)
2-Piperidones were prepared bearing heptanoic acid or a thioether heptanoic acid at the 1-position as well as appropriately substituted at the 6-position to mimic the structure of prostaglandins. The stereochemical purity at the 6-position was determined to be ≥95% ee for an advanced synthetic intermediate. The 2-piperidones were identified as potent agonists at the EP4 prostanoid receptor. They displayed a high affinity (K i 5-130 nM) at EP4 and subtype selectivity.
